Results 61 to 70 of about 20,792 (192)

Phylogenetic and recombinant analyses of complete coding sequences of DENV-1 from field-caught mosquitoes in Thailand

Virus Research, 2020
Dengue diseases are a group of infectious diseases that have been widespread throughout the world for several decades. Dengue outbreaks have occurred in many parts of the world, including Southeast Asia. The outbreak and the severity of the diseases depend on many factors including dengue genotype.
Vitara, Punpapong, Thikhumporn, Sittivicharpinyo, Passorn, Wonnapinij, Wunrada, Surat   +3 more
openaire   +2 more sources

Predominance of Dengue Virus Serotype-1/Genotype-I in Eastern and Southeastern Ethiopia

Viruses
We determined the dengue virus (DENV) serotypes and genotypes in archived serum samples that were collected during the 2014–2016 and 2021 dengue outbreaks in Dire Dawa City and the Somali region in Ethiopia.
Mesfin Mengesha Tsegaye, Adamu Tayachew Mekonnen, Daniel Tsega Gebretsion, Tesfaye Gelanew, Dawit Hailu Alemayehu, Dessalegn Abeje Tefera, Tamirayehu Seyoum Woldemichael, Bethlehem Adnew Getaneh, Eleni Kidane Abera, Gadissa Gutema Jebessa, Asefa Konde Korkiso, Mengistu Biru Tessema, Admikew Agunie Asfaw, Yoseph Asrat Temre, Mesfin Wossen, Anne Piantadosi, Huachen Zhu, Alemseged Abdissa, Adane Mihret, Andargachew Mulu   +19 more
doaj   +1 more source

Phylogenetic analysis revealed the co-circulation of four dengue virus serotypes in Southern Thailand.

PLoS ONE, 2019
Dengue fever is caused by dengue viruses (DENV) from the Flavivirus genus and is the most prevalent arboviral disease. DENV exists in four immunogenically distinct and genetically-related serotypes (DENV-1 to 4), each subdivided in genotypes. Despite the
Rodolphe Hamel, Pornapat Surasombatpattana, Sineewanlaya Wichit, Alexandra Dauvé, Celeste Donato, Julien Pompon, Dhanasekaran Vijaykrishna, Florian Liegeois, Ronald Morales Vargas, Natthanej Luplertlop, Dorothée Missé   +10 more
doaj   +1 more source

Host‐Directed Antiviral Activity of SB2960 Through Selective Induction and Remodeling of Stress Granules

Advanced Science, EarlyView.
Amid the ongoing threat of emerging viral pathogens, host‐directed antivirals offer a strategy to overcome viral mutation and drug resistance. SB2960, a small‐molecule inducer of stress granules (SGs), exhibits potent broad‐spectrum antiviral activity with minimal cytotoxicity.
Wan Gi Byun, Sumin Son, JinAh Lee, Minha Lee, Meehyun Ko, Songrui Zhao, Ju Hee Kim, Kannan Vaithegi, Ji Hoon Kwon, Jung Ho Lee, Sangeun Jeon, Dawon Yi, Peng Zou, Seungtaek Kim, Seung Bum Park   +14 more
wiley   +1 more source

Dengue virus type 1 (DENV-1) TaqMan (DENV1-TM2017) assay v2

, 2018
This protocol was designed and developed at this laboratory. The assay specifically targets the 3' UTR region of DENV-1 and is designed as a qualitative screening test for human cases of DENV-1 infection, but not other known DENVs.
Ian M Mackay, Judy A Northill
openaire   +1 more source

Population dynamics of DENV-1 genotype V in Brazil is characterized by co-circulation and strain/lineage replacement [PDF]

Archives of Virology, 2012
Following successive outbreaks of dengue fever caused predominantly by dengue virus (DENV) 2 and 3, DENV-1 is now the primary serotype circulating in Brazil. We sequenced and analyzed Brazilian DENV-1 genomes and found that all isolates belong to genotype V and are subdivided into three lineages, which were introduced during four different events.
Drumond, Betânia Paiva, Mondini, Adriano, Schmidt, Diane J., Bosch, Irene, Nogueira, Maurício Lacerda   +4 more
openaire   +3 more sources

Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1

Advanced Science, EarlyView.
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang, Yi Liu, Zhiying Yao, Haolong Lai, Xiaoxin Chen, Ziqiu Wang, Yiqiong Bao, Tingting Li, Xiaoming Zhou, Xiabin Chen, Peiguo Yang   +10 more
wiley   +1 more source

Factores de riesgo a la exposición al virus DENV 1-4

Revista Digital de Postgrado
Objetivo: Evaluar los factores de riesgo a la exposición de virus de dengue en el Municipio Chacao entre enero y marzo de 2024. Método: La población objeto de la presente investigación estuvo conformada por todos los habitantes del municipio Chacao atendidos en los distintos ambulatorios de Salud Chacao durante los meses enero ...
Enni Sousa De Leonardis, Janett Virginia Pérez Rivas   +1 more
openaire   +2 more sources

In Silico Comparative Analysis of Predicted B Cell Epitopes against Dengue Virus (Serotypes 1–4) Isolated from the Philippines

Vaccines, 2022
Dengue is a viral mosquito-borne disease that rapidly spreads in tropical and subtropical countries, including the Philippines. One of its most distinguishing characteristics is the ability of the Dengue Virus (DENV) to easily surpass the innate ...
Lyn Marielle I. Abesamis, Evan Gilles A. Aliping, Fritz Khrystian Gabriel H. Armada, Mirriam F. Danao, Pamela Denise B. del Valle, Zypher Jude G. Regencia, Emmanuel S. Baja, Antonio D. Ligsay   +7 more
doaj   +1 more source

Membralin Assembles a MAN1B1–VCP Complex to Target Foreign Glycoproteins from the Endoplasmic Reticulum to Lysosomes for Degradation

Advanced Science, EarlyView.
This study identifies Membralin as an ER‐phagy receptor that recruits MAN1B1 and VCP to form a selective ERLAD complex. By sensing dense N‐glycan clusters on viral fusion glycoproteins, this ubiquitin‐independent pathway directs SARS‐CoV‐2 spike, Ebola GP, influenza HA, and HIV‐1 Env to lysosomal degradation, thereby limiting viral infectivity ...
Jing Zhang, Xiaoran Lu, Sunan Li, Tao Wang, Iqbal Ahmad, Yong‐Hui Zheng   +5 more
wiley   +1 more source