Results 141 to 150 of about 102,850,963 (222)
SB203580 treatment reduces DENV-induced liver pathology in DENV-infected mice.
, 2016 Mice were infected with DENV and treated with 2%DMSO or SB203580 dissolved in 2%DMSO. The uninfected control group was also treated with 2%DMSO. Seven days after infection, liver tissues were collected in 10% formalin for histopathological analysis and H&
Sansanee Noisakran (109150) +6 more
core +1 more source
Population dynamics of DENV-1, DENV-2 and DENV-3 circulating lineages in Brazil.
, 2014 Panel A shows the proportion of federal states (total of 27) where each DENV serotype was molecularly confirmed from 2002 to 2012. Panels B, C and D depict changes in effective population size (Ne) over time (dashed lines) respectively for DENV-1, DENV-2
Nuno Rodrigues Faria (554050) +13 more
core +1 more source
Scientific ReportsThe mosquito transmitted dengue virus (DENV) is a major public health problem in many tropical and sub-tropical countries around the world. Both vaccine development and drug development are complex as the species Dengue virus consist of four distinct ...
Chanida Chumchanchira +5 more
doaj +1 more source
Primer sequences for the DENV multiplex rRT-PCR.
, 2013 Genomic locations are provided for the 5′ base of each primer based on reference virus sequences: DENV-1, US/Hawaii/1944 (GenBank: EU848545.1); DENV-2, New Guinea C Strain (GenBank: AF038403.1); DENV-3, strain H87 (GenBank: M93130.1); DENV-4, strain H241
Jesse J. Waggoner (404050) +14 more
core +1 more source
Phylogenetic tree of DENV-2 from Lihir, October 2010.
, 2018 PNG DENV-2 (indicated in red) compared with reference viruses obtained from GenBank. The Lihir virus grouped with the Cosmopolitan genotype of DENV-2, and clustered with DENV-2 identified in travellers entering northern Australia from PNG 2009–2010.
Shannon Bennett (478668) +7 more
core +1 more source
, 2018 Analysis of the correlation between DENV-specific IgG responses and (A) degree of viraemia (Spearmans r = -0.25, p = 0.16) in patients with DHF, (B) degree of thrombocytopenia (Spearmans r = -0.29, p = 0.009), (C) aspartate transaminase (AST) levels ...
Clare S. Hardman (5807009) +9 more
core +1 more source
Localization of Wolbachia and DENV-2 in Ae. albopictus.
, 2013 At 14 days post-DENV-2 infection, salivary glands were dissected, fixed, and then incubated simultaneously with two Wolbachia probes and two DENV specific probes. In panels A, B, and C, DENV-2 (green) is labeled with FITC.
Patrick Mavingui (190877) +5 more
core +1 more source
Innate immune response during DENV-2 infection of monocytes/macrophages
, 2022 ABSTRACT: The pathogenesis of DENV infection is characterized by a dysregulated inflammatory response and a transient increase in endothelial permeability. Monocytes and macrophages play an essential role during innate immune response against DENV infection, as they are innate sentinels and contribute to viral clearance.
openaire +1 more source
Archives of VirologyAbstract Dengue virus (DENV) continues to pose a significant global health threat, with increasing infection rates and limited treatment options. The viral NS2B-NS3 protease (NS2B-NS3pro), a highly conserved two-component enzyme essential for polyprotein processing and replication, is a key target for antiviral drug ...
Haojia Zhu +13 more
openaire +2 more sources
IFN-α treatment and activated pDC coculture in DENV-2-infected monocytes.
, 2013 Freshly purified monocytes were infected with DENV-2 (MOI 10) for 48 hours, pre-treated or not with IFN-α. (A) Nucleus/DAPI (blue) and virus (green) of monocytes mock- (upper panels) or DENV-2-infected (lower panels). Viral particles were detected in the
Christophe Gras (418897) +9 more
core +1 more source