Results 61 to 70 of about 102,850,963 (222)
Iflaviruses in arthropods: when small is mighty
Insect Science, EarlyView.Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia +3 more
wiley +1 more source
, 2013 The linear range for the multiplex rRT-PCR assay is shown for DENV-1 (A), DENV-2 (B), DENV-3 (C), and DENV-4 (D).
Jesse J. Waggoner (404050) +14 more
core +1 more source
PLOS Neglected Tropical Diseases, 2021 Dengue is one of the most prevalent arthropod-borne viral diseases in humans. There is still no effective vaccine or treatment to date. Previous studies showed that mosquito-derived factors present in saliva or salivary gland extract (SGE) contribute to the pathogenesis of dengue.
Ka Wan Cheang +3 more
openaire +4 more sources
Liver Organoids: From Disease Modelling to Regenerative Medicine
Cell Proliferation, EarlyView.Liver organoids provide a versatile platform for disease modelling and drug discovery, leveraging stem cells and engineering techniques. They bridge research and clinical applications, offering significant potential for advancing precision medicine and regenerative therapies for liver diseases.
Tiepeng Wang +5 more
wiley +1 more source
Model of infectious intracellular transport of DENV-1 HW, DENV-2 NGC and DENV-2 16681 in Vero cells.
, 2013 DENV-1 HW is internalized through the classical clathrin-mediated endocytic pathway, while DENV-2 NGC and DENV-2 16681 use a non-classical clathrin- and caveolin- independent route.
Elsa B. Damonte (308403) +2 more
core +1 more source
Scientific Reports, 2022 A large national outbreak of chikungunya virus (CHIKV) was recently reported in Thailand. While dengue virus (DENV) infection tends to occur year-round with an upsurge in the rainy season, Zika virus (ZIKV) also circulates in the country.
Sarawut Khongwichit +3 more
doaj +1 more source
Innate immune responses of monocytes/macrophages to DENV-2 infection
, 2022 The pathogenesis of severe DENV infection is characterized by a dysregulated inflammatory response and a transient increase in endothelial permeability. Monocytes and macrophages play an essential role in the innate immune response towards DENV and also represent an important target cell for virus replication.
openaire +2 more sources
Contribution of endosomal proteins EHD1 and EHD4 to the HIV‐1 replication cycle
The FEBS Journal, EarlyView.EHD1 and EHD4, two key trafficking proteins, regulate multiple stages of HIV‐1 infection: In producer cells, they help produce fully infectious virus particles, regulate Envelope protein incorporation in a cell‐type‐dependent manner, and limit the accumulation of antiviral IFITM proteins in virions.
Grégory Pacini +4 more
wiley +1 more source
DENV-3 plasmid starting library.
, 2017 DENV-3 antigen fragment plasmid library was assessed by Ion Torrent Deep Sequencing to determine coverage at each amino acid position. (A) Deduced peptide sequences were aligned to the DENV-3 polyprotein with NCBI BLAST and used to determine the coverage
Kathryn M. Frietze (3713686) +4 more
core +1 more source
Predominance of Dengue Virus Serotype-1/Genotype-I in Eastern and Southeastern Ethiopia
VirusesWe determined the dengue virus (DENV) serotypes and genotypes in archived serum samples that were collected during the 2014–2016 and 2021 dengue outbreaks in Dire Dawa City and the Somali region in Ethiopia.
Mesfin Mengesha Tsegaye +19 more
doaj +1 more source