Results 41 to 50 of about 102,850,963 (222)
The number of peptides and epitopes detected by the serum samples from dengue and Zika patients in the E and NS1 proteins of DENV-1, DENV-2, DENV-3, DENV-4, and ZIKV.
Luiz Tadeu Moraes Figueiredo (8119802) +7 more
core +1 more source
Recombinant DENV 2 NS5: An effective antigen for diagnosis of DENV infection
Dengue fever is a mosquito-borne viral disease with dramatically increasing morbidity rate worldwide in decades. Since there is no specific treatment to date, early diagnosis is important for providing proper timely medical care to minimize mortality, and for the prompt initiation of public health control measures.
Ting Zhang +9 more
openaire +2 more sources
DENV-specific IgG, but not IgA, mediates ADE in U937 cells.
A) Quantification of FcγRIIa (CD32), FcγRI (CD64), FcαR (CD89), and DC-SIGN (CD209) expression on U937 cells by flow cytometry. Histogram labels are isotype control-subtracted geometric mean fluorescence intensity (MFI) values.
Adam D. Wegman (11750252) +6 more
core +1 more source
Structural similarities between Zika (ZIKV) and dengue virus (DENV) leads to the induction of cross-reactive responses. We have previously demonstrated that ZIKV exposed macaques significantly enhance DENV viremia.
William G. Valiant +5 more
doaj +1 more source
Spatiotemporal Dynamics of DENV-2 Asian-American Genotype Lineages in the Americas
The Asian/American (AS/AM) genotype of dengue virus type 2 (DENV-2) has been evolving in the Americas over the last 30 years, leading to several waves of dengue epidemics and to the emergence of different viral lineages in the region. In this study, we investigate the spatiotemporal dissemination pattern of the DENV-2 lineages at a regional level.
Daiana Mir +3 more
openaire +4 more sources
Endurance, Refuge, and Reemergence of Dengue Virus Type 2, Puerto Rico, 1986–2007
To study the evolution of dengue virus (DENV) serotype 2 in Puerto Rico, we examined the genetic composition and diversity of 160 DENV-2 genomes obtained through 22 consecutive years of sampling.
Kate L. McElroy +5 more
doaj +1 more source
Dengue virus neutralizing antibody levels associated with protection from infection in thai cluster studies. [PDF]
Long-term homologous and temporary heterologous protection from dengue virus (DENV) infection may be mediated by neutralizing antibodies. However, neutralizing antibody titers (NTs) have not been clearly associated with protection from infection.Data ...
Darunee Buddhari +13 more
doaj +1 more source
Superficial vimentin mediates DENV-2 infection of vascular endothelial cells
Abstract Damage to vascular endothelial cells (VECs) is a critical hallmark of hemorrhagic diseases caused by dengue virus (DENV). However, the precise molecular event involved in DENV binding and infection of VECs has yet to be clarified.
Jie Yang +10 more
openaire +2 more sources
Sera collected 2 weeks after DENV inoculation were tested by plaque-reduction neutralization test (PRNT) for their neutralizing activity against DENV-1 60305, DENV-2 44/2, DENV-3 16562 and DENV-4 TVP360.
Michael Cruz (5142977) +16 more
core +1 more source
DENV-2 RNA levels increase WT and SK1-/- mice following ic DENV infection.
WT and SK1-/- mice were ic infected with DENV, as in Fig 1. RNA was isolated from infected mice brain tissues and analysed by real time qRT-PCR for DENV. A. Total DENV-2 RNA increases with time in WT mice, n = 3 at each time point; B.
Jennifer N. Clarke (403889) +5 more
core +1 more source

