ZIKV infection activates the IRE1-XBP1 and ATF6 pathways of unfolded protein response in neural cells. [PDF]
, 2018 BACKGROUND: Many viruses depend on the extensive membranous network of the endoplasmic reticulum (ER) for their translation, replication, and packaging. Certain membrane modifications of the ER can be a trigger for ER stress, as well as the accumulation ...
Fu, Z +11 more
core +1 more source
Superficial vimentin mediates DENV-2 infection of vascular endothelial cells
Scientific Reports, 2016 AbstractDamage to vascular endothelial cells (VECs) is a critical hallmark of hemorrhagic diseases caused by dengue virus (DENV). However, the precise molecular event involved in DENV binding and infection of VECs has yet to be clarified. In this study, vimentin (55 kDa) was identified to be involved in DENV-2 adsorption into VECs.
Jie Yang +10 more
openaire +2 more sources
Arbovirus emergence in the temperate city of Córdoba, Argentina, 2009-2018 [PDF]
, 2019 The distribution of arbovirus disease transmission is expanding from the tropics and subtropics into temperate regions worldwide. The temperate city of Córdoba, Argentina has been experiencing the emergence of dengue virus, transmitted by the mosquito ...
Benitez, Elisabet Marina +6 more
core +2 more sources
Molecular epidemiology of American/Asian genotype DENV-2 in Peru
Infection, Genetics and Evolution, 2013 During the past decade, countries in South America have reported dengue hemorrhagic fever (DHF) associated with American/Asian genotype of dengue virus serotype 2 (DENV-2). DENV-2 strains have been associated with large outbreaks of dengue fever and DHF in numerous regions of Peru since the mid-1990s, but studies to address the origins, distribution ...
Cristhopher D, Cruz +6 more
openaire +2 more sources
Inhibition of dengue virus replication by novel inhibitors of RNA-dependent RNA polymerase and protease activities [PDF]
, 2017 Dengue virus (DENV) is the leading mosquito-transmitted viral infection in the world. With more than 390 million new infections annually, and up to 1 million clinical cases with severe disease manifestations, there continues to be a need to develop new ...
Coluccia, A. +9 more
core +1 more source
Investigação de polimorfismos no genoma do vírus da Dengue
RECIIS, 2007 O presente estudo teve como objetivo caracterizar qualitativamente e quantitativamente o polimorfismo entre os quatro genótipos do vírus da Dengue - DENV-1, DENV-2, DENV-3 e DENV-4.
Roberto Fabian Santos de Araújo +3 more
doaj +1 more source
Intracranial Injection of Dengue Virus Induces Interferon Stimulated Genes and CD8+ T Cell Infiltration by Sphingosine Kinase 1 Independent Pathways [PDF]
, 2017 Copyright: © 2017 Al-Shujairi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and ...
Al-Shujairi, Wisam H +5 more
core +4 more sources
Complete Coding Sequences of Five Dengue Virus Type 2 Clinical Isolates from Venezuela Obtained through Shotgun Metagenomics [PDF]
, 2018 Dengue is a disease endemic in Latin American countries, like Venezuela, and has become one of the most important public health problems. We report five complete coding sequences of dengue virus serotype 2 (DENV-2) isolated from DENV-infected patients in
Couto, Natacha +7 more
core +2 more sources
Broad Dengue Neutralization in Mosquitoes Expressing an Engineered Antibody [PDF]
, 2020 With dengue virus (DENV) becoming endemic in tropical and subtropical regions worldwide, there is a pressing global demand for effective strategies to control the mosquitoes that spread this disease.
Akbari, Omar S. +11 more
core +4 more sources
Wolbachia versus dengue: Evolutionary forecasts. [PDF]
, 2013 A novel form of biological control is being applied to the dengue virus. The agent is the maternally transmitted bacterium Wolbachia, naturally absent from the main dengue vector, the mosquito Aedes aegypti.
Bull, James J, Turelli, Michael
core +1 more source