Latar belakang. Dengue adalah infeksi virus akut dengan 4 serotipe virus. Penelitian seroprevalensi pada anak di Indonesia menunjukkan terdapat perubahan pola serotipe dengue dari berbagai daerah di Indonesia. Tujuan.
Edi Hartoyo, Lina Purnamasari
doaj +1 more source
Geraniin extracted from the rind of Nephelium lappaceum binds to dengue virus type-2 envelope protein and inhibits early stage of virus replication [PDF]
Background: The rapid rise and spread in dengue cases, together with the unavailability of safe vaccines and effective antiviral drugs, warrant the need to discover and develop novel anti-dengue treatments.
Chew, Miaw Fang * +5 more
core +1 more source
Phylogeography of Recently Emerged DENV-2 in Southern Viet Nam
يعد الكشف عن انتشار فيروسات حمى الضنك (DENV) في الزمان والمكان أمرًا أساسيًا لفهم علم الأوبئة الخاص بها. ومع ذلك، فإن العمليات التي تشكل أنماط انتقال DENV على نطاق السكان المحليين ليست مفهومة جيدًا، لا سيما تأثير عوامل مثل حركة السكان البشريين والتحضر.
Maia A. Rabaa +5 more
openaire +6 more sources
Inhibition of type I interferon induction and signalling by mosquito-borne flaviviruses [PDF]
The Flavivirus genus (Flaviviridae family) contains a number of important human pathogens, including dengue and Zika viruses, which have the potential to cause severe disease.
Clark, Jordan J. +3 more
core +1 more source
Screening for differentially expressed miRNAs in Aedes albopictus (Diptera: Culicidae) exposed to DENV-2 and their effect on replication of DENV-2 in C6/36 cells [PDF]
The mosquito Aedes albopictus is an important vector for dengue virus (DENV) transmission. The midgut is the first barrier to mosquito infection by DENV, and this barrier is a critical factor affecting the vector competence of the mosquito. However, the molecular mechanism of the interaction between midgut and virus is unknown.Six small libraries of Ae.
Jianxin Su +9 more
openaire +3 more sources
Circulation of Different Lineages of Dengue Virus 2, Genotype American/Asian in Brazil: Dynamics and Molecular and Phylogenetic Characterization [PDF]
The American/Asian genotype of Dengue virus type 2 (DENV-2) was introduced into the Americas in the 80′s. Although there is no data showing when this genotype was first introduced into Brazil, it was first detected in Brazil in 1990.
A Mondini +45 more
core +5 more sources
Prevalence of Dengue Serotype (DENV-2) in Pakistan
Dengue is one of the leading cause of death worldwide. The first outbreak of dengue hemorrhagic fever was reported in 1994 in Pakistan and after that several outbreaks of the dengue were reported in Pakistan and in all these outbreaks, the dengue serotype 2 (DENV2) was confirmed, which ensures that dengue serotype 2 (DENV2) is prevalent in Pakistan.
Naveed Akhtar +3 more
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Modified mRNA-LNP Vaccines Confer Protection against Experimental DENV-2 Infection in Mice [PDF]
Dengue virus (DENV) infection is a major global public health concern, and there is no effective vaccine for it. In this study, we describe the design and characterization of three nucleotide-modified mRNA vaccines (prME-mRNA, E80-mRNA, and NS1-mRNA) for DENV-2.
Mengling Zhang, Jin Sun, Min Li, Xia Jin
openaire +3 more sources
Concurrent infection with dengue virus type-2 and DENV-3 in a patient from Ceará, Brazil
Dengue outbreaks have occurred in several regions in Brazil and cocirculating dengue virus type 1 (DENV-1), DENV-2, and DENV-3 have been frequently observed.
Fernanda Montenegro de Carvalho Araújo +6 more
doaj +1 more source
Vimentin Inhibits Dengue Virus Type 2 Invasion of the Blood-Brain Barrier
Dengue virus (DENV) causes dengue fever, which is prevalent in the tropical and subtropical regions, and in recent years, has resulted in several major epidemics. Vimentin, a cytoskeletal component involved in DENV infection, is significantly reorganized
Jianhai Yu +11 more
doaj +1 more source

