Results 41 to 50 of about 69,682 (133)

How Should Thiopurine Treatment be Monitored? Methodological Aspects

, 2010
Monitoring of thiopurine metabolites is important due to a complex metabolism with large interindividual variation, but the suitability of currently used methods has been questioned.
Peterson, Curt,, Vikingsson, Svante,, Almer, Sven, Carlsson, Björn, Vikingsson, Svante, Peterson, Curt, Almer, Sven,, Carlsson, Björn,   +7 more
core   +1 more source

Molecular analysis of mammalian adenylyl cyclases and bacterial adenylyl cyclase toxins [PDF]

, 2009
The cAMP signaling pathway is crucial for many physiological processes and many disease states like neurodegenerative diseases, mood disorders, pain, drug dependency or heart failure.
Göttle, Martin
core   +1 more source

Nucleotides: Structure and Properties [PDF]

, 2005
Nucleotides consist of a nitrogen-containing base, a five-carbon sugar, and one or more phosphate groups. Cells contain many types of nucleotides, which play a central role in a wide variety of cellular processes, including metabolic regulation and the ...
Richard Peter Bowater, Bowater, RP
core   +1 more source

Effect of cyclic nucleotides on the production of albumin and fibrinogen by rat hepatocytes in primary culture.

, 1978
The effects of cyclic nucleotides on the production of albumin and fibrinogen by rat hepatocytes in primary culture are preliminarily ...
E. NEGRI, E. DRAGHI, P. G. ANDREIS, ARMATO, Ubaldo   +3 more
core   +1 more source

Thermal Diffusion of Nucleotides

, 2012
We investigate the thermal diffusion behavior of aqueous solutions of nucleotides using an infrared thermal diffusion forced Rayleigh scattering (IR-TDFRS) setup.
Kriegs, H., Wiegand, S., Wang, Z.
core   +1 more source

Distributions of P nucleotides.

, 2012
(A) Histogram of the average palindrome length frequencies at four coding ends of the V(D)J rearrangement in the naïve and memory CD8+ T cells of seven healthy donors and the naïve and memory CD4+ T cell of six donors.
Santosh K. Srivastava (110172), Harlan S. Robins (110176)   +1 more
core   +1 more source

Profiling of Sugar Nucleotides

, 2017
Sugar nucleotides are essential building blocks for the glycobiology of all living organisms. Detailed information on the types of sugar nucleotides present in a particular cell and how they change as a function of metabolic, developmental, or disease ...
Wagstaff, Ben A., Hill, L., Lionel Hill, Wagstaff, B.A., Robert A. Field, Martin Rejzek, Rejzek, Martin, Rejzek, M., Field, Robert A., Edward S. Hems, Sakonwan Kuhaudomlarp, Ben A. Wagstaff, Kuhaudomlarp, S., Hems, E.S., Kuhaudomlarp, Sakonwan, Hems, Edward S., Field, R.A.; id_orcid, Hill, Lionel   +17 more
core   +1 more source

Intracellular ATP influences synaptic plasticity in area CA1 of rat hippocampus via metabolism to adenosine and activity-dependent activation of adenosine A1 receptors [PDF]

, 2011
The extent to which brain slices reflect the energetic status of the in vivo brain has been a subject of debate. We addressed this issue to investigate the recovery of energetic parameters and adenine nucleotides in rat hippocampal slices and the ...
D. Grahame Hardie, Hardie, D. G. (D. Grahame), Naomi Pentland, Simon Hawley, Frenguelli, Bruno, Doney, Alexander S., Pentland, Naomi, Frenguelli, Bruno G., Stephanie zur Nedden, Hawley, Simon, Alexander S. Doney, Bruno G. Frenguelli, Hardie, D. Grahame, Doney, Alexander S.; id_orcid, Zur Nedden, Stephanie   +14 more
core   +1 more source

Changes in cardiac nucleotide metabolism in Huntington’s disease [PDF]

, 2016
Huntington’s disease (HD) is a monogenic neurodegenerative disorder with a significant peripheral component to the disease pathology. This includes an HD-related cardiomyopathy, with an unknown pathological mechanism.
Slominska, E, Smolenski, R, Isalan, M, Kutryb-Zajac, B, Zukowska, P, Mielcarek, M, Toczek, M   +6 more
core   +1 more source

Nucleotides as Bacterial Second Messengers

, 2023
In addition to comprising monomers of nucleic acids, nucleotides have signaling functions and act as second messengers in both prokaryotic and eukaryotic cells. The most common example is cyclic AMP (cAMP).
Claudia Guerrero-Barajas, Juan C. Cancino-Diaz, Gabriel Betanzos-Cabrera, Mario E. Cancino-Diaz   +3 more
core   +1 more source