Modification of Pyrimidine and Purine Nucleotides By Click Chemistry: Design, Synthesis and Properties Study [PDF]
, 2014 This dissertation consists of three main parts, totaling five chapters, and focuses on developing novel nucleosides via click chemistry and studying their potential biological properties. Chapter three describes the synthesis and properties of coumarin-
Haque, Mohammad Mojibul
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Cruciform Extrusion in Methylation-State Variants of pBR322 Plasmid [PDF]
, 2007 The presence of DNA secondary structures in genomic DNA has been observed in both prokaryotes and eukaryotes. Specifically, sections of ssDNA may melt out and form cruciform/hairpin structures within palindromic sequences or areas of high purine content.
McElwain, Lucas Morgan
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A Single-Molecule Nanopore Device Detects DNA Polymerase Activity with Single-Nucleotide Resolution [PDF]
, 2008 The ability to monitor DNA polymerase activity with single-nucleotide resolution has been the cornerstone of a number of advanced single-molecule DNA sequencing concepts.
Amorin, Manuel +4 more
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Detection of minimal numbers of neoplastic cells carrying DNA translocations by DNA sequence amplification [PDF]
, 1991 The present invention related to a sensitive method of detecting t(14;18) translocations arising from variable breakpoints in the J-region of the immunoglobulin heavy chain locus on chromosome 14.
Lee, Ming-Sheng
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Synthesis of fluorinated nucleosides for probing DNA conformations via 19F NMR spectroscopy [PDF]
, 2019 Work described in this thesis explored the synthesis of 5-fluoro-2’-deoxycytidine and 8-fluoro-2’-deoxyguanosine, and subsequent incorporation of these modified nucleosides into d(CG) repeat oligonucleotides through the phosphoramidite chemistry-based ...
Solodinin, Andrei
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Absence of arsenate in DNA from arsenate-grown GFAJ-1 cells
, 2012 A strain of Halomonas bacteria, GFAJ-1, has been reported to be able to use arsenate as a nutrient when phosphate is limiting, and to specifically incorporate arsenic into its DNA in place of phosphorus.
Cotner +8 more
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Genetic improvement and utilisation of indigenous tilapia in southern Africa: final technical report, December 1st 1998 to June 31st, 2002 [PDF]
, 2002 Mozambique tilapia (Oreochromis mossambicus) is an indigenous tilapia species in southern Africa, until now the majority of genetic research has been carried out on Asian species of tilapia but this project aims to look at this African species.
Beardmore, J.A. +3 more
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Full length genome characterisation of Hepatitis B virus isolates at Dr George Mukhari Hospital in Pretoria, South Africa [PDF]
, 2011 Thesis (MSc. (Medical Virology))-- University of Limpopo, 2011.Introduction: Sub-Saharan Africa is a region with hepatitis B virus (HBV) hyperendemicity with more than 8% HBsAg prevalence.
Magobo, Rindidzani Edith
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Visualizing Allele Specific Expression In Single Cells [PDF]
, 2016 Single molecule RNA FISH techniques have enabled the quantification of gene expression at the single cell level, revealing significant variability that has been previously obscured by techniques measuring population averages.
Ginart, Paul
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Using Selective Enzymes to Measure Noncanonical DNA Building Blocks: dUTP, 5-Methyl-dCTP, and 5-Hydroxymethyl-dCTP. [PDF]
Biomolecules, 2023 Surányi ÉV +7 more
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