Results 1 to 10 of about 29,276 (194)

Association of sirtuin 1 rs10997868 and rs730821 polymorphisms with sirtuin 1 and hydroxy-2′-deoxyguanosine levels in healthy smokers: A case–control study [PDF]

Journal of International Medical Research
Objectives This case–control study explored the association of sirtuin 1 polymorphisms (rs10997868 and rs730821) with metabolic parameters, smoking duration, sirtuin 1 levels, and the oxidative stress biomarker 8-hydroxy-2′-deoxyguanosine in healthy ...
Samar Sultan
doaj   +2 more sources

8-Oxo-7,8-dihydro-2'-deoxyguanosine Forms a Relatively Unstable Tetrameric Structure Compared with 2'-Deoxyguanosine

Journal of Clinical Biochemistry and Nutrition, 2009
The hydrogen-bonded guanine tetrad, or G-quartet has been implicated in a variety of biological roles, including the function of chromosome telomeres. Here effect of the hydroxylation of guanosine at the 8 position on the G-quartet formation was examined.
Hideo Iwahashi
openalex   +4 more sources

Enzymatic Cleavage of Deoxyguanosine Triphosphate to Deoxyguanosine and Tripolyphosphate

Journal of Biological Chemistry, 1958
S.R. Kornberg, I Lehman, Maurice Bessman, Ernest S. Simms, Arthur Kornberg   +4 more
openalex   +3 more sources

Determining 8-oxo-2’-deoxyguanosine/2’-deoxyguanosine ratio in DNA by reverse phase HPLC combined with amperometric detection

Тонкие химические технологии, 2010
The article presents an optimized method for the determination of the ratio of 8-oxo-2'-deoxyguanosine (formed in DNA due to the action of active forms of oxygen) to 2'-deoxyguanosine.
D. S. Esipov, E. V. Sidorenko, O. V. Esipova, T. A. Gorbacheva, T. S. Nevredimova, A. L. Krushinskiy, V. S. Kuzenkov, V. P. Reutov   +7 more
doaj   +1 more source

Staphylococcus aureus Multiplexes Death-Effector Deoxyribonucleosides to Neutralize Phagocytes

Frontiers in Immunology, 2022
Adenosine synthase A (AdsA) is a key virulence factor of Staphylococcus aureus, a dangerous microbe that causes fatal diseases in humans. Together with staphylococcal nuclease, AdsA generates deoxyadenosine (dAdo) from neutrophil extracellular DNA traps ...
Eshraq Tantawy, Eshraq Tantawy, Nicoletta Schwermann, Nicoletta Schwermann, Tjorven Ostermeier, Tjorven Ostermeier, Annette Garbe, Heike Bähre, Marius Vital, Volker Winstel, Volker Winstel   +10 more
doaj   +1 more source

Molecular Identification of the Transient Species Mediating the Deactivation Dynamics of Solvated Guanosine and Deazaguanosine

Molecules, 2022
Small structural alterations of the purine/pyrimidine core have been related to important photophysical changes, such as the loss of photostability. Similarly to canonical nucleobases, solute-solvent interactions can lead to a change in the excited state
Javier Ortín-Fernández, Jesús González-Vázquez, Lara Martínez-Fernández, Inés Corral   +3 more
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The Status of Antioxidants and Oxidative Damage in Patients with COVID-19

Ahi Evran Medical Journal, 2023
Purpose: COVID-19 is a viral disease that has recently caused a pandemic and significantly affects human health. In this study, superoxide dismutase, glutathione peroxidase, glutathione, total thiol, natural thiol, disulfide, oxidative DNA damage and ...
İrfan BİNİCİ, Hamit Hakan ALP, Zübeyir HUYUT, Esra GÜRBÜZ, Hülya GÜNBATAR, Şükrü AKMEŞE, Mustafa Kasım KARAHOCAGİL, Halil İbrahim AKBAY   +7 more
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Deoxyguanosine kinase deficiency and recurrent spontaneous pneumothorax: a case report

Journal of Medical Case Reports, 2023
Background Deoxyguanosine kinase deficiency is mainly manifested by hepatic and neurological damage, hence it belongs to the hepatocerebral form of mitochondrial deoxyribonucleic acid depletion syndrome.
Alice Ramboux, Alain Poncelet, Philippe Clapuyt, Isabelle Scheers, Etienne Sokal, Raymond Reding, Xavier Stephenne   +6 more
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8-Fluoro-N-2-Isobutyryl-2′-Deoxyguanosine: Synthesis and Reactivity

Molbank, 2020
3′,5′-O-Bis(tert-butyldimethylsilyl)-8-fluoro-N-2-isobutyryl-2′-deoxyguanosine was synthesized from 3′,5′-O-bis(tert-butyldimethylsilyl)-N-2-isobutyryl-2′-deoxyguanosine by the treatment with N-fluorobenzenesulfonimide.
Andrei Solodinin, James Helmkay, Samuel Ollivier, Hongbin Yan   +3 more
doaj   +1 more source

Widely targeted metabolomics reveals the antioxidant and anticancer activities of different colors of Dianthus caryophyllus

Frontiers in Nutrition, 2023
Carnation is edible flower that has potent antioxidant properties and is used in traditional Chinese medicinal system and food industry. The phytochemicals responsible for these various proprieties, however, are not fully understood.
Xuhong Zhou, Xuhong Zhou, Miaomaio Wang, Hong Li, Shilong Ye, Wenru Tang   +5 more
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