Results 201 to 210 of about 47,583 (239)
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Acta Crystallographica Section C Crystal Structure Communications, 2005
In the title compound, 2-amino-7-(2-deoxy-beta-D-erythro-pentofuranosyl)-3,7-dihydropyrrolo[2,3-d]pyrimidin-4-one, C11H14N4O4, the N-glycosylic bond torsion angle, chi, is anti [-106.5 (3) degrees ]. The 2'-deoxyribofuranosyl moiety adopts the 3T4 (N-type) conformation, with P = 39.1 degrees and tau(m) = 40.3 degrees .
Henning Eickmeier +2 more
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In the title compound, 2-amino-7-(2-deoxy-beta-D-erythro-pentofuranosyl)-3,7-dihydropyrrolo[2,3-d]pyrimidin-4-one, C11H14N4O4, the N-glycosylic bond torsion angle, chi, is anti [-106.5 (3) degrees ]. The 2'-deoxyribofuranosyl moiety adopts the 3T4 (N-type) conformation, with P = 39.1 degrees and tau(m) = 40.3 degrees .
Henning Eickmeier +2 more
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Modification of deoxyguanosine by chloroethylene oxide
Carcinogenesis, 1981Reaction of deoxyguanosine in glacial acetic acid with chloroethylene oxide, a proposed reactive metabolite of vinyl chloride, led to a single, strongly fluorescent product in nearly quantitative yield. The u.v. spectra indicated alkylation of N-7 of guanine, which was confirmed following reduction of the reaction product by sodium borohydride to 7-(2 ...
C.J.Der Van Laken +4 more
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ChemInform Abstract: Reaction of 2′‐Deoxyguanosine with Glucose. [PDF]
ChemInform, 1995 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Stefan Ochs, Theodor Severin
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Archives of Biochemistry and Biophysics, 1987
That deoxyguanosine is taken up by isolated rat liver mitochondria has been shown. This report describes the relationship between that uptake and oxidative phosphorylation. By measuring this process in the presence of standard inhibitors of oxidative phosphorylation it was determined that a functional electron transport chain, but not the ...
Roger A. Lewis, Linda F. Watkins
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That deoxyguanosine is taken up by isolated rat liver mitochondria has been shown. This report describes the relationship between that uptake and oxidative phosphorylation. By measuring this process in the presence of standard inhibitors of oxidative phosphorylation it was determined that a functional electron transport chain, but not the ...
Roger A. Lewis, Linda F. Watkins
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Deoxyguanosine kinase from human placenta
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1982Deoxyguanosine kinase (ATP:deoxyguanosine 5'-phosphotransferase) has been purified up to a specific activity of 10.3 nmol/min per mg protein from human placenta. The enzyme appears to have a molecular weight of 58 000 from the results of Sephadex G-75 gel filtration.
Nobuaki Ogasawara +2 more
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Journal of Inorganic Biochemistry, 2007
The metal ions Cu(II), Fe(II), and Cr(III) were allowed to react with H(2)O(2) in the presence of either the mononucleoside 2'-deoxyguanosine (dG) or the mononucleotide 2'-deoxyguanosine-5'-monophosphate (dGMP). The percentage of reacted dG or dGMP that formed the oxidative damage marker 8-hydroxy-2'-deoxyguanosine (8-OH-dG) was monitored.
Noblitt, Scott D. +2 more
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The metal ions Cu(II), Fe(II), and Cr(III) were allowed to react with H(2)O(2) in the presence of either the mononucleoside 2'-deoxyguanosine (dG) or the mononucleotide 2'-deoxyguanosine-5'-monophosphate (dGMP). The percentage of reacted dG or dGMP that formed the oxidative damage marker 8-hydroxy-2'-deoxyguanosine (8-OH-dG) was monitored.
Noblitt, Scott D. +2 more
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Structure of a neothramycin-2′-deoxyguanosine adduct
Biochemical and Biophysical Research Communications, 1981Abstract The interaction of neothramycin, a pyrrolo (1,4)benzodiazepine antibiotic with antitumor activity, with deoxyribonucleosides was studied as a model of the drug-DNA binding. The antibiotic was demonstrated to react with 2′-deoxyguanosine in aqueous dimethyl sulfoxide. Two reaction products were found on thin-layer plates.
Nobuo Tanaka +3 more
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Hydroxylation of Deoxyguanosine in DNA by Copper and Thiols
Archives of Biochemistry and Biophysics, 1995DNA was incubated with glutathione (GSH) and copper and then assayed for 8-hydroxydeoxyguanosine (8-OHdG) in order to better understand the antioxidant and prooxidant characteristics of GSH in copper-dependent DNA damage. Ratios of GSH to Cu(II) less than 3 resulted in 8-OHdG production; however, higher ratios did not generate 8-OHdG.
S.D. Aust, Nathan Spear
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Regioselective 1‐Alkylation of 2′‐Deoxyguanosine.
ChemInform, 2002AbstractFor Abstract see ChemInform Abstract in Full Text.
Yanhe Huang, Francis Johnson
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Chemico-Biological Interactions, 1990
The rates of degradation of N-7 platinated deoxyguanosine (dG) and deoxyguanylyl-(3'-5')-deoxyguanosine (dGpdG) were followed in 66 mM Tris-HCl (pH 7.4) at 100 degrees C. The half-life for the intramolecular cross-link of cis-diamminedichloroplatinum(II) (cis-Pt) between two neighboring guanines (Pt-dGpdG) was 86 min, and the half-life of the ...
Kari Hemminki +2 more
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The rates of degradation of N-7 platinated deoxyguanosine (dG) and deoxyguanylyl-(3'-5')-deoxyguanosine (dGpdG) were followed in 66 mM Tris-HCl (pH 7.4) at 100 degrees C. The half-life for the intramolecular cross-link of cis-diamminedichloroplatinum(II) (cis-Pt) between two neighboring guanines (Pt-dGpdG) was 86 min, and the half-life of the ...
Kari Hemminki +2 more
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