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Benzimidazoles as novel deoxyribonuclease I inhibitors
Journal of Cellular Biochemistry, 2018AbstractInhibitory potential of 19 benzimidazoles against bovine pancreatic deoxyribonuclease I (DNase I) was investigated in vitro. Three compounds inhibited DNase I with IC50 below 100 μM and proved to be more potent DNase I inhibitors than crystal violet (IC50 = 351.82 ± 29.41 μM), used as a positive control.
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