Results 21 to 30 of about 65 (48)

Safety evaluation of the food enzyme pectin lyase from the non‐genetically modified Aspergillus luchuensis strain CBS 141530

EFSA Journal, Volume 24, Issue 7, July 2026.
Abstract The food enzyme pectin lyase (1,4‐6‐O‐methyl‐α‐D‐galacturonan lyase; EC 4.2.2.10) is produced with the non‐genetically modified Aspergillus luchuensis strain CBS 141530 by Solyve. The food enzyme was considered free from viable cells of the production organism. It is intended to be used in 12 food manufacturing processes.
EFSA Panel on Food Enzymes (FEZ), Holger Zorn, José Manuel Barat Baviera, Claudia Bolognesi, Francesco Catania, Gabriele Gadermaier, Ralf Greiner, Baltasar Mayo, Alicja Mortensen, Yrjö Henrik Roos, Marize L. M. Solano, Henk Van Loveren, Laurence Vernis, Cristina Andreoli, Andrea Terron, Andrey Yurkov, Magdalena Andryszkiewicz, Daniele Cavanna, Natalia Kovalkovicova, Yi Liu   +19 more
wiley   +1 more source

Safety evaluation of the food enzyme pectin lyase from the genetically modified Aspergillus niger strain CCTCC M 2023341

EFSA Journal, Volume 24, Issue 7, July 2026.
Abstract The food enzyme pectin lyase (1,4‐6‐O‐methyl‐α‐d‐galacturonan lyase, EC 4.2.2.10) is produced with the genetically modified Aspergillus niger strain CCTCC M 2023341 by Suntaq International Limited. The genetic modifications do not give rise to safety concerns. The food enzyme was considered free from viable cells of the production organism and
EFSA Panel on Food Enzymes (FEZ), Holger Zorn, José Manuel Barat Baviera, Claudia Bolognesi, Francesco Catania, Gabriele Gadermaier, Ralf Greiner, Baltasar Mayo, Alicja Mortensen, Yrjö Henrik Roos, Marize L. M. Solano, Monika Sramkova, Henk Van Loveren, Laurence Vernis, Cristina Andreoli, Andrea Terron, Ana Criado, Valentina Tokić, Cristina Fernández‐Fraguas, Yi Liu, Silvia Peluso, Daniele Cavanna   +21 more
wiley   +1 more source

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, Volume 4, Issue 2, June 2026.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

Persistent Fluorodeoxyglucose Uptake on Post‐Definitive Radiotherapy PET/CT Evaluation Predicts Poor Survival in Pediatric Metastatic Ewing Sarcoma: A Single‐Center Cohort Study

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Though 18F‐FDG‐PET CT scan is established as a standard of care imaging technique for staging and restaging in Ewing Sarcoma (ES), its utility in the prognostic assessment of residual masses post definitive radiotherapy to the primary is still unknown. This study audits the above. Procedure Children ≤ 15 years of age with ES treated
Badira Cheriyalinkal Parambil, Sneha Shah, Nilendu Purandare, Maya Prasad, Venkata Rama Mohan Gollamudi, Siddhartha Laskar, Nehal Khanna, Jifmi Jose Manjali, Amit Janu, Vasundhara Patil, Akshay Baheti, Mukta Ramadwar, Poonam Panjwani, Bharat Rekhi, Bhanupriya Sandupatla, Rajeswari Arul, Venkatesh Rangarajan, Girish Chinnaswamy   +17 more
wiley   +1 more source

Metal‐dependent regulated cell death: Molecular architecture and translational frontiers

iMeta, Volume 5, Issue 3, June 2026.
Intracellular metal dyshomeostasis orchestrates distinct regulated cell death programs, including iron‐driven ferroptosis, copper‐mediated cuproptosis, calcicoptosis, newly designated zincoptosis, mnoptosis, and coptosis. This review systematically delineates their molecular architectures—spanning from Sorafenib‐induced lipid peroxidation and ...
Haoliang Hu, Zhe Chen, Yaqi Li, Jiayi Peng, Jiangang Cao, Hong Zhou, Mengqi Wang, Yuejia Du, Hailin Wu, Huiqin Zhao, Shifang Huang, Dianmei Yu, Meiqing Liu, Olga V. Shevchenko, Natalia Yu. Matveeva, Yiyuan Yang, Kerui Huang, Deguan Lv, Junxia Min, Linxi Chen, Fudi Wang   +20 more
wiley   +1 more source

Role of the UHRF1–KLHL6–CORO2B axis in obesity‐related insulin resistance

Journal of Diabetes Investigation, Volume 17, Issue 6, Page 920-937, June 2026.
In high‐fat diet (HFD)‐induced obese mice with insulin resistance, overexpression of UHRF1 may recruit DNMT1 to promote DNA methylation of KLHL6, leading to its downregulation. Subsequently, suppression of KLHL6 may decrease the ubiquitination of CORO2B, resulting in elevated CORO2B protein levels.
Xu Deng, Xiaoping Li, Jialuo Cai, Xinyu Chen, Zelin Xu, Yuntao Luo   +5 more
wiley   +1 more source

Early Radiation Therapy Response Assessment Using Multi‐Scale Photoacoustic Imaging

Advanced Science, Volume 13, Issue 26, 8 May 2026.
Tomographic and mesoscopic photoacoustics capture intratumoural features of radioresistance and response. ABSTRACT There is a critical unmet clinical need to identify biomarkers that predict and detect radiation therapy (RT) response in cancer. Using the unique capabilities of multi‐scale photoacoustic imaging (PAI) to depict tumor oxygenation and ...
Thierry L. Lefebvre, Mariam‐Eleni Oraiopoulou, Ellie V. Bunce, Thomas R. Else, Lorna C. Wright, Monika A. Golinska, Lina Hacker, Cara Brodie, Steven Kupczak, Yi Cheng, Lisa Young, Paul W. Sweeney, Sarah E. Bohndiek   +12 more
wiley   +1 more source

m5C‐Modified tRF3b‐CysGCA‐23 Suppresses Bladder Cancer Malignancy by Repressing H3K18 Lactylation via Stabilizing RBM4

Advanced Science, Volume 13, Issue 26, 8 May 2026.
In this study, we identified an NSUN6‐dependent m5C‐modified tsRNA, m5C‐tRF3b CysGCA‐23 (mtRC), that is downregulated in BC and inversely correlated with disease progression. Mechanistically, mtRC suppresses BC malignancy by stabilizing RBM4, attenuating glycolysis, and thereby limiting H3K18 lactylation–mediated activation of IL1RAP and VASH2 ...
Xiaoling Ying, Yapeng Huang, Jian Huang, Qinyu Cai, Danni Zhang, Cong Chen, Yuxi Nie, Baotong Yang, Chuan Li, Wenyu Hu, Chang Xiong, Chengcheng Zhang, Ding Ji, Yaomin Liang, Mei Yang, Wenqi Wu, Weidong Ji   +16 more
wiley   +1 more source

Integral attacks on reduced-round Deoxys-BC and RAIN algorithms

Tongxin xuebao
Considering the impact of tweakeys on tweakable block cipher algorithms, achieved integral attacks on Deoxys-BC and RAIN algorithms by combining zero-correlation linear cryptanalysis with integral attacks and utilizing partial-sum technique. 176 types of
Du Xiaoni, Guan Xueying, Yu Tian, Liang Lifang   +3 more
doaj  

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source