Results 81 to 90 of about 670,645 (305)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Dependency-based LSTM model.

open access: yes, 2018
The D-LSTM uses a LSTM to read in word vectors and employs its final hidden state as a basic component vbasic for each sentence. The D-LSTM performs a dependency parse on the input sentence and generates the supporting component vsupp for each sentence ...
Tengjun Yao (4919728)   +4 more
core   +1 more source

Indicating Dependency between Spoken Sentences by Prosodic Means

open access: yesDiscours, 2018
In certain languages and in certain types of data, prosodic features are used to group prosodic units called by some scholars spoken sentences into larger units, often called speech paragraphs.
Mari Wiklund
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Impact of Spouse's Opiate Dependence on the Partner's

open access: yesJournal of Family and Reproductive Health, 2008
Objective: We aimed to evaluate the influence of drug dependency on sexual function of wives of opium addicts. Materials and methods: In a cross-sectional study, 150 wives of opiate dependent men were assessed for the impact of drug addiction ...
Roya Noori   +5 more
doaj  

The Limits to Dependent Growth in East-Central Europe

open access: yesRevue de la Régulation, 2018
Between 1990 and 2017 the four central eastern European countries (CEECs), Czechia, Hungary, Poland and Slovakia narrowed the gap in economic levels with the EU average.
Martin Myant
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Chaste/dependency-modules: v0.1.3

open access: yes
<h2>What's Changed</h2> <ul> <li>Updated minimum supported library versions (see below) in https://github.com/Chaste/dependency-modules/pull/67</li> <li>Attached "oldest-boost" tag to a portability docker ...
Gary Mirams, Kwabena N Amponsah
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Dependency-aware software release planning

open access: yes, 2017
Dependency-aware software release ...
Davoud Mougouei (14681671)   +2 more
core  

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