Results 51 to 60 of about 5,883,864 (257)

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng   +3 more
wiley   +1 more source

Kasei-Theory: Structural Dependency Articulation [PDF]

open access: yes
This paper articulates structural dependency in Kasei-Theory. Dependency is not introduced as a causal, temporal, or functional relation.
Minamikata, Juza
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Franz Hinkelammert (1931-2023). Biografía intelectual y contribuciones al pensamiento crítico latinoamericano desde una teología profana

open access: yesRevista Iberoamericana de Estudios de Desarrollo
As a tribute, in memory of Franz Hinkelammert, this article constructs an intellectual story of his life articulated in five stages, from his birth in 1931 to his death in 2023.
Antonio Luis Hidalgo-Capitán   +1 more
doaj   +1 more source

A New Approach to Bivariate Transmutation: Construction of Continuous Bivariate Distribution Under Negative Dependency

open access: yesCumhuriyet Science Journal, 2020
In this study, a new approach to transmutation theory is developed by using negative dependency basement. Once choosing a distribution that has negative dependency with the same marginal, a new bivariate distribution is derived.
Mehmet Yılmaz, Hüseyin Ünözkan
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

The unequal costs of war: income inequality amid the Russia–Ukraine conflict [PDF]

open access: yesJournal of Economics and Development
PurposeThis study analyses how the Russia–Ukraine war reshaped income inequality dynamics across 10 post-Soviet economies, focussing on whether pre-existing structural dependency conditions influenced the transmission of geopolitical shocks into domestic
Jomana M. Eissa
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Home - About - Disclaimer - Privacy