Results 61 to 70 of about 87,543 (295)
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Dependency theory and economic growth
This thesis examines the concept of dependency theory between developing and developed countries. Formerly popular concept explains reasons of underdevelopment in poor countries. This work discusses about two main approaches as the structuralism and neo-
Béreš, Adam
core +1 more source
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Liberation and dependency: a theological reading of social sciences in Latin America
Introduction: In the early 1970s, social movements directed Latin American theologyto a creative process of deprivatization of the Christian faith, reconfiguring fromthe community practices of liberation and their holistic implications the ...
Teixeira, Helio Aparecido Campos +1 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
This article examines the publication practices in the field of communication and media studies (CMS) by analyzing the main patterns and features of Scopus-indexed journals.
Marton Demeter
doaj
Diffusion of Innovation vs. Dependence Theory: FinTech Inclusion in the AfCFTA Era
The African Continental Free Trade Area (AfCFTA) aspires to accelerate digital financial integration across Africa, yet the diffusion of FinTech innovations shows uneven patterns shaped by deep-seated power structures.
Sixbert SANGWA +2 more
doaj +1 more source

