Results 71 to 80 of about 87,543 (295)

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Economic Development and Dependence Theory: The Approach of the Un Economic Commission for Latin America and the Caribbean (ECLAC)

open access: yesStudia Ekonomiczne i Regionalne, 2018
Subject and purpose of work: The purpose of this article is to present the vision of ECLAC - Economic Commission for Latin America and the Caribbean and its contribution to the reflections on economic development.
Bonzanini Osmar Antonio   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

SME Choice of Direct and Indirect Export Modes: Resource Dependency and Institutional Theory Perspectives [PDF]

open access: yes
This paper develops and tests resource dependency and institutional theory arguments for explaining two choices facing SMEs: the decision to export or not, and, in case a firm has decided to export, the choice between exporting directly or indirectly. We
Siri Terjesen, Jolanda Hessels
core  

Unequal Exchange with Differential Ground Rent: The Originality of Uruguayan Dependency Theory

open access: yesAlternautas
Historiography on Latin American dependency theory highlights its importance between the sixties and eighties, primarily focusing on Chilean and Brazilian perspectives.
Pablo Messina
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Existence dependency: conceptual modelling by contract. [PDF]

open access: yes
In Object Orientation, the Generalisation/Specialisation hierarchy and the Whole/Part relationship are prevalent classification schemes for object types.
Dedene, Guido, Snoeck, Monique
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Unpacking AI Chatbot Dependency: A Dual-Path Model of Cognitive and Affective Mechanisms

open access: yesInformation
With AI chatbots becoming increasingly embedded in everyday life, growing concerns have emerged regarding users’ psychological dependency on these systems.
Na Zhai, Xiaomei Ma, Xiaojun Ding
doaj   +1 more source

Home - About - Disclaimer - Privacy