Results 81 to 90 of about 5,687,485 (286)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Book review of: Vania Bambirra, (1978). Teoría de la dependencia: una anticrítica. Ediciones Era. México D.F.

open access: yesAlternautas
In her 1978 short book Teoría de la Dependencia: Una Anticrítica Brazilian scholar Vania Bambirra responds to the most prominent critiques during the middle of the ‘70s about Dependency Theory. In line with a fertile trend in Marxist critical literature,
Andrea Taborri
doaj   +1 more source

Economic Development and Dependence Theory: The Approach of the Un Economic Commission for Latin America and the Caribbean (ECLAC)

open access: yesStudia Ekonomiczne i Regionalne, 2018
Subject and purpose of work: The purpose of this article is to present the vision of ECLAC - Economic Commission for Latin America and the Caribbean and its contribution to the reflections on economic development.
Bonzanini Osmar Antonio   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

SME Choice of Direct and Indirect Export Modes: Resource Dependency and Institutional Theory Perspectives [PDF]

open access: yes
This paper develops and tests resource dependency and institutional theory arguments for explaining two choices facing SMEs: the decision to export or not, and, in case a firm has decided to export, the choice between exporting directly or indirectly. We
Siri Terjesen, Jolanda Hessels
core  

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Unpacking AI Chatbot Dependency: A Dual-Path Model of Cognitive and Affective Mechanisms

open access: yesInformation
With AI chatbots becoming increasingly embedded in everyday life, growing concerns have emerged regarding users’ psychological dependency on these systems.
Na Zhai, Xiaomei Ma, Xiaojun Ding
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

The DCU dependency-based metric in WMT-MetricsMATR 2010 [PDF]

open access: yes, 2010
We describe DCU’s LFG dependencybased metric submitted to the shared evaluation task of WMT-MetricsMATR 2010. The metric is built on the LFG F-structurebased approach presented in (Owczarzak et al., 2007).
He, Yifan   +3 more
core   +3 more sources

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