Results 81 to 90 of about 87,543 (295)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The impact of pro-vulnerable income transfers : Leisure, dependency and a distribution hypothesis [PDF]
This paper studies a transmission mechanism through which pro-vulnerable income transfers may affect individual decision-making of non-beneficiaries in an extreme poverty context, leading to labor supply contraction and the so-called dependency syndrome.
Limodio, Nicola
core
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
"Capitalism, Culture, Agency: Dependency Versus Postcolonial Theory" [PDF]
, 2002 This article reads dependency alongside and against postcolonial theory in an attempt to reinvigorate and re-validate some of the insights of the former while at the same time supporting the latter's current ascendancy in the field of Third World ...
Kapoor, Ilan
core
Dependency Theory and the Aesthetics of Contrast in Fernando Solanas’s La hora de los hornos and Memoria del saqueo [PDF]
, 2008 This paper is a comparative analysis of two key documentaries by Fernando Solanas: La hora de los hornos / The Hour of the Furnaces (1966–68) and Memoria del saqueo / Social Genocide (2003).
Olivera, Guillermo Elpidio
core +1 more source
APORTES DE RUY MAURO MARINI AO DEBATE SOBRE O ESTADO NOS PAÍSES DEPENDENTES
Caderno CRHNo presente artigo, lançamos nosso olhar para uma temática de especial relevância para o contexto político atual latino-americano – o Estado. Ao revisitar os escritos de Ruy Mauro Marini, uma das principais referências da Teoria Marxista da Dependência ...
Maíra Machado Bichir
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source