Protocol for chemogenetic activation of basal ganglia D1-MSNs and behavioral assessments in a primate Parkinson's disease model. [PDF]
Chen Y+14 more
europepmc +1 more source
Protocol for the intracerebral injection of AAV-α-synuclein plus poly(ADP-ribose) to generate a Parkinson's disease monkey model. [PDF]
Liu S, Si W, Wang Z.
europepmc +1 more source
Endothelial-to-mesenchymal transition enhances permissiveness to AAV vectors in cardiac endothelial cells. [PDF]
Volf N+10 more
europepmc +1 more source
Designing and optimizing AAV-mediated gene therapy for neurodegenerative diseases: from bench to bedside. [PDF]
Xu L+8 more
europepmc +1 more source
Chronic Hepatitis B Genotype C Mouse Model with Persistent Covalently Closed Circular DNA. [PDF]
Seo DH+7 more
europepmc +1 more source
Focused ultrasound widely broadens AAV-delivered Cas9 distribution and activity. [PDF]
Gumusgoz E+13 more
europepmc +1 more source
Rational design of a Lfng-enhancer AAV construct drives specific and efficient gene expression in inner ear supporting cells. [PDF]
Seist R, Copeland JS, Tao L, Groves AK.
europepmc +1 more source
Viral mediated α-synuclein overexpression results in greater transgene levels and α-synuclein overload in mice bearing kinase dead mutation of LRRK2. [PDF]
Albanese F+6 more
europepmc +1 more source
Idebenone vs. rAAV2-ND4 gene therapy in the treatment of Leber's hereditary optic neuropathy: An indirect comparison meta-analysis. [PDF]
Hassan AK, Abu Serhan H.
europepmc +1 more source
Delivery of a Muscle-Targeted Adeno-Associated Vector Via <i>Ex Vivo</i> Normothermic Perfusion Is Efficient, Durable, and Safe in a Preclinical Porcine Heart Transplant Model. [PDF]
Dewan KC+19 more
europepmc +1 more source