Results 51 to 60 of about 6,309 (150)
Role of the vector genome and underlying factor IX mutation in immune responses to AAV gene therapy for hemophilia B [PDF]
, 2014 BACKGROUND: Self-complementary adeno-associated virus (scAAV) vectors have become a desirable vector for therapeutic gene transfer due to their ability to produce greater levels of transgene than single-stranded AAV (ssAAV).
Ashley T Martino +4 more
core +1 more source
Cloning and sequencing of the simian parvovirus genome.
Virology, 1995 We recently reported the identification of a novel simian parvovirus in cynomolgus monkeys with severe anemia. We now describe the cloning and sequencing of 4986 nucleotides of the viral DNA.
K. Brown +3 more
semanticscholar +1 more source
MOLECULAR MECHANISMS OF THE DNA DAMAGE RESPONSE INDUCED DURING PARVOVIRUS INFECTION [PDF]
, 2012 DNA damage response (DDR) is a critical safeguarding system to protect genomic stability and integrality through a cascade of phosphorylation events of three PI-3-kinase-like kinases: ATM (ataxia telangiectasia mutated), ATR (ATM and Rad3 related), and ...
Luo, Yong
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Viruses Infecting Reptiles [PDF]
, 2011 A large number of viruses have been described in many different reptiles. These viruses include arboviruses that primarily infect mammals or birds as well as viruses that are specific for reptiles.
Marschang, Rachel E.
core +3 more sources
ОНКОЛИТИЧЕСКИЕ ПАРВОВИРУСЫ. НОВЫЕ ПОДХОДЫ К ЛЕЧЕНИЮ РАКОВЫХ ЗАБОЛЕВАНИЙ [PDF]
, 2012 Parvoviruses such as parvovirus H-1 (H-1PV) may selectively infect and lysis cancer cells. The parvoviruses also induce an immune system to eliminate the tumor cells through the formation of anti-cancer immunity.
Chumakov P.M. +3 more
core +2 more sources
The Sero-Prevalence of Parvovirus Antibodies among Children with Sickle Cell Anaemia in Zaria [PDF]
, 2012 Parvovirus is an erythrovirus that infects red cell precursors in individuals with conditions characterised by a high red cell turnover like sickle cell anaemia and thalassaemia. Arthritis, vasculitis, carditis, bone marrow failure, and the slapped cheek
Aliyu, A +3 more
core +2 more sources
Princípios de terapia génica [PDF]
, 2016 Podríamos definir la terapia génica como la introducción de un gen foráneo en el ser humano con fines terapéuticos. La terapia génica comenzó a ser utilizada en el ser humano a principios de los años 90 y en los últimos años ha empezado a dar sus frutos.
Reverter Velasco, Naiara
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Gene Delivery into the Central Nervous System (CNS) Using AAV Vectors [PDF]
, 2015 Application of gene therapies is a promising approach to the treatment of various neurological disorders, including Parkinson\u27s disease, amyotrophic lateral sclerosis (ALS), and lysosomal storage disorders, which are not treatable by any other means ...
Miyake, Koichi +2 more
core +1 more source
Класифікація вірусів людини і тварин [PDF]
, 2015 У навчально-методичних рекомендаціях викладено основи загальної вірусології щодо морфології та хімічного складу вірусів, механізму їх репродукції. Розглянуто сучасну класифікацію вірусів і таксономічну характеристику родин вірусів людини і тварин, де ...
Holub, Serhii M. +7 more
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Класифікація вірусів людини і тварин [PDF]
, 2012 У навчально-методичних рекомендаціях викладено основи загальної вірусології щодо морфології та хімічного складу вірусів, механізму їх репродукції. Розглянуто сучасну класифікацію вірусів і таксономічну характеристику родин вірусів людини і тварин, де ...
Holub, Olena S. +7 more
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