Results 131 to 140 of about 205,153 (377)

Dynamics of post-translational modification systems: recent progress and future directions

, 2017
Post-translational modification (PTM) of proteins plays a key role in signal transduction, and hence significant effort has gone toward understanding how PTM networks process information. This involves, on the theory side, analyzing the dynamical systems
Conradi, Carsten, Shiu, Anne
core   +1 more source

The Gut Commensal Butyricimonas Virosa Modulates Gut Microbiota‐Dependent Thiamine Metabolism and Attenuates Mouse Steatotic Liver Disease

Advanced Science, EarlyView.
This study reveals that dietary stachyose enriches Butyricimonas virosa, effectively attenuating metabolic dysfunction‐associated steatotic liver disease (MASLD). Mechanistically, B. virosa enhances gut thiamine monophosphate synthesis, which elevates hepatic thiamine pyrophosphate levels.
Ningning He, Haoyu Wang, Zizhen Yang, Hui Li, Bei Liu, Kaiwei Chen, Zhinan Wu, Xinnan Zhao, Hewei Liang, Mengmeng Wang, Xiaofang Li, Yiyi Zhong, Haifeng Zhang, Liang Xiao, Karsten Kristiansen, Jixing Peng, Yuanqiang Zou, Shangyong Li   +17 more
wiley   +1 more source

Editorial: Protein phosphorylation and dephosphorylation in plant-microbe interactions

Frontiers in Plant Science, 2022
Jianbin Su, Yi-Ju Lu, Yi-Ju Lu, Yi-Ju Lu, Jens Staal, Jens Staal, Agnieszka Ludwików   +6 more
doaj   +1 more source

Protein Phosphatase 2A Enhances the Proapoptotic Function of Bax through Dephosphorylation [PDF]

, 2006
Meiguo Xin, Xingming Deng
openalex   +1 more source

p38 Mitogen-activated protein kinase pathway suppresses cell survival by inducing dephosphorylation of mitogen-activated protein/extracellular signal-regulated kinase kinase1,2.

Cancer Research, 2020
Song-ping Li, M. Junttila, Jiahuai Han, V. Kähäri, J. Westermarck   +4 more
semanticscholar   +1 more source

RNA polymerase II termination involves CTD tyrosine dephosphorylation by CPF subunit Glc7

Nature Structural &Molecular Biology, 2014
At the 3′ ends of protein-coding genes, RNA polymerase (Pol) II is dephosphorylated at tyrosine residues (Tyr1) of its C-terminal domain (CTD). In addition, the associated cleavage-and-polyadenylation factor (CPF) cleaves the transcript and adds a poly(a)
A. Schreieck, A. Easter, S. Etzold, K. Wiederhold, Michael Lidschreiber, P. Cramer, L. A. Passmore   +6 more
semanticscholar   +1 more source

Surface Engineered Biomolecular Condensates for Targeted Cell Cytotoxicity

Advanced Science, EarlyView.
Interfacial engineering of biomolecular condensates with a decanoic acid (DA) membrane enables molecular‐weight‐gated enzyme localization. Small biomolecules (≤60 kDa) enrich internally, while high‐molecular‐weight alkaline phosphatase (ALP) localizes at the interface.
Chengying Yin, Cheng Wu, Xinran Yu, Yifeng Zhu, Baohu Wu, Yue Wang, Liangfei Tian   +6 more
wiley   +1 more source

In silico, in vitro and cellular analysis with a kinome-wide inhibitor panel correlates cellular LRRK2 dephosphorylation to inhibitor activity on LRRK2

Frontiers in Molecular Neuroscience, 2014
Leucine-rich repeat kinase 2 (LRRK2) is a complex, multidomain protein which is considered a valuable target for potential disease-modifying therapeutic strategies for Parkinson's disease (PD).
R. Vancraenenbroeck, J. De Raeymaecker, Evy Lobbestael, Fangye Gao, M. de Maeyer, A. Voet, V. Baekelandt, J. Taymans   +7 more
semanticscholar   +1 more source

Nanozymes Integrated Biochips Toward Smart Detection System

Advanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen, Wang Zheng, Zhihui Zhang, Shenping Yu, Xinxin Hang, Han Wu, Xiao‐Wei Xiang, Wei Mu, Yanli Jiao, Zaizai Dong, Lingqian Chang   +10 more
wiley   +1 more source

Prostate Cancer Dephosphorylation Atlas [PDF]

, 2011
The widespread nature of protein phosphorylation/dephosphorylation underscores its key role in cell metabolism. Phosphate moiety balance on proteins is regulated by protein kinases (PK) and protein phosphatases (PP), which are milestone players of eukaryotic signaling pathways.
Ferreira, Carmen Veríssima, Milani, Renato, Zambuzzi, Willian Fernando, Halder, Thomas Martin, Galembeck, Eduardo, Aoyama, Hiroshi   +5 more
openaire   +2 more sources