Results 201 to 210 of about 205,153 (377)

Specific dephosphorylation by phosphatases 1 and 2A of a nuclear protein structurally and immunologically related to nucleolin [PDF]

, 1989
Helge R. Schneider, Gottfried Mieskes, Olaf‐Georg Issinger   +2 more
openalex   +1 more source

Across species: A comparative perspective on red cell homeostasis and its influence on our understanding of human physiology and disease

British Journal of Haematology, EarlyView.
This review highlights how studies on animal red cells have enriched our understanding of the behaviour of those from humans. A comparative perspective has enhanced our knowledge of human red cell pathophysiology Summary This review emphasises how studies on animal red cells have enriched our understanding of the behaviour of those from humans.
Kathleen M. Connolly, Pengyi Ding, Rasiqh Wadud, David C. Rees, John N. Brewin, John S. Gibson   +5 more
wiley   +1 more source

Exploring the interplay between protein conformational changes and phosphorylation in a pancreatic cancer cell and stellate cell coculture system. [PDF]

Proc Natl Acad Sci U S A
Lu H, Liu Y, Chiang HY, Zhang H, Shi X, Li L.   +5 more
europepmc   +1 more source

Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria

Proceedings of the National Academy of Sciences of the United States of America, 2008
G. Cereghetti, A. Stangherlin, O. Brito, Chuang-Rung Chang, C. Blackstone, P. Bernardi, L. Scorrano   +6 more
semanticscholar   +1 more source

Protein tyrosine phosphatases as emerging targets for cancer immunotherapy

British Journal of Pharmacology, EarlyView.
Abstract Contemporary strategies in cancer immunotherapy, despite remarkable success, remain constrained by inherent limitations such as suboptimal patient responses, the emergence of drug resistance, and the manifestation of pronounced adverse effects. Consequently, the need for alternative strategies for immunotherapy becomes clear.
Zihan Qu, Jiajun Dong, Zhong‐Yin Zhang
wiley   +1 more source

Phosphatase PP2A promotes RTA dephosphorylation to impair KSHV lytic replication. [PDF]

PLoS Pathog
Bai L, Dong L, Dong J, Liang X, Peng J, Chen Y, Sun X, Chen Y, Li X, Cai H, Huang J, Cao Z, Lan K.   +12 more
europepmc   +1 more source

MYC dephosphorylation by the PP1/PNUTS phosphatase complex regulates chromatin binding and protein stability [PDF]

, 2018
Dharmendra Dingar, William B. Tu, Diana Resetca, Corey Lourenco, Aaliya Tamachi, Jason De Melo, Kathleen E. Houlahan, Manpreet Kalkat, Pak-Kei Chan, Paul C. Boutros, Brian Raught, Linda Z. Penn   +11 more
openalex   +1 more source

The impact of Foxp3+ regulatory T‐cells on CD8+ T‐cell dysfunction in tumour microenvironments and responses to immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy, inducing durable remissions in responding patients. However, they are associated with variable outcomes, spanning from disease hyperprogression to complete responses with the onset of immune‐related adverse events.
Mikhaël Attias, Ciriaco A. Piccirillo
wiley   +1 more source

Enarodustat suppresses thymic stromal lymphopoietin expression via hypoxia-inducible factor-mediated c-Jun N-terminal kinases dephosphorylation. [PDF]

PLoS One
Segawa R, Yagisawa M, Miyata C, Hirasawa N.   +3 more
europepmc   +1 more source

Compartmentalisation in cAMP signalling: A phase separation perspective

British Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source