Results 211 to 220 of about 205,153 (377)

Greatwall dephosphorylation and inactivation upon mitotic exit is triggered by PP1

open access: yesJournal of Cell Science, 2016
Sheng-Mei Ma   +6 more
semanticscholar   +1 more source

Songorine inhibits mitophagy in chronic heart failure via the TBC1D15/Fis1/Rab7A pathway

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and purpose Songorine (SGR) is an alkaloid extracted from Aconitum carichaelii Debx. and has a demonstrated role in cardiac dysfunction. Chronic heart failure (CHF) is a severe clinical syndrome leading to functional impairment and death, primarily due to the deterioration of energy metabolism in cardiomyocytes. However, the precise
Wenxiu Liu   +4 more
wiley   +1 more source

Termination of the integrated stress response. [PDF]

open access: yesScience
De Miguel C   +5 more
europepmc   +1 more source

Leucine induced dephosphorylation of Sestrin2 promotes mTORC1 activation.

open access: yesCellular Signalling, 2016
S. Kimball   +4 more
semanticscholar   +1 more source

Sodium butyrate ameliorates renal tubular lipid accumulation through a protein phosphatase 2A/transcription factor EB axis in diabetic nephropathy

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Extensive evidence indicates that lipid accumulation causes renal tubular injury, which further contributes to diabetic nephropathy (DN) progression. Short‐chain fatty acids (SCFAs) play an important role in the maintenance of cellular metabolic health.
Jiayin Tao   +12 more
wiley   +1 more source

A composite motif in calcimembrin/C16orf74 dictates multimeric dephosphorylation by calcineurin. [PDF]

open access: yesNat Commun
Bradburn DA   +6 more
europepmc   +1 more source

FB23‐2 and Cisplatin Synergize to Inhibit Head and Neck Squamous Cell Carcinoma by Targeting the XPF/ERCC1 Complex

open access: yesCancer Science, EarlyView.
FB23‐2 potentiates cisplatin's antitumor efficacy in head and neck squamous cell carcinoma by disrupting XPF/ERCC1 complex assembly and nuclear translocation, thereby suppressing DNA damage repair machinery and amplifying platinum‐induced tumor cell death.
Yaoqi Jiang   +7 more
wiley   +1 more source

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