Results 271 to 280 of about 205,153 (377)

Understanding the dynamic nature of plant lipid anabolic and catabolic metabolism is key to sustainable oilseed engineering

New Phytologist, EarlyView.
Summary Plant‐derived oils are essential sources of reduced carbon and various fatty acid (FA) structures for food, biofuels, and the oleochemical industry. Despite extensive efforts, engineering mainstream oilseed crops to produce high levels of industrially valuable unusual FAs (UFAs) remains challenging.
Prasad Parchuri, Sean T. McGuire, Matthew G. Garneau, Niña Alyssa M. Barroga, Philip D. Bates   +4 more
wiley   +1 more source

Functional Analysis of a Homozygous MYBPC3 Null Allele in Human Pediatric Patients. [PDF]

Circ Res
Bennett JS, Wood PT, Dominic KL, Moravec CS, Campbell KS, Stelzer JE.   +5 more
europepmc   +1 more source

The Complex Relation of Branched‐Chain Amino Acids and Inflammation in the Obesity and Diabetes Context

Obesity Reviews, EarlyView.
ABSTRACT In a scenario with increasing cases of obesity and diabetes worldwide, branched‐chain amino acids (BCAA) metabolism has become an important factor in the understanding of these pathologies. More recently, its chronic high plasma levels have been postulated, alongside glucose, inflammatory factors, and other molecules, as an important ...
Bernardo Starling‐Soares, Monique Macedo Coelho, Bruna Guerra Campolina, Camila Kümmel Duarte, Tatiani Uceli Maioli   +4 more
wiley   +1 more source

Activity Deprivation Modulates the Shank3/Homer1/mGluR5 Signaling Pathway to Enable Synaptic Upscaling. [PDF]

J Neurosci
Guerrero AA, Turrigiano GG.
europepmc   +1 more source

Dephosphorylation and inactivation of NPR2 guanylyl cyclase in granulosa cells contributes to the LH-induced decrease in cGMP that causes resumption of meiosis in rat oocytes

Development, 2014
J. Egbert, Leia C. Shuhaibar, Aaron B. Edmund, D. Van Helden, J. Robinson, T. Uliasz, V. Baena, A. Geerts, F. Wunder, L. Potter, L. Jaffe   +10 more
semanticscholar   +1 more source

Mandibular Condylar Cartilage in Development and Diseases: A PTHrP‐Centric View

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT The mandibular condylar cartilage (MCC) is a dual‐function component of the temporomandibular joint (TMJ), acting as both articular cartilage for jaw movement and growth cartilage for vertical growth of the mandibular condyle. Parathyroid hormone‐related protein (PTHrP) plays a critical role in orchestrating chondrogenesis in the long bone ...
Chiaki Tsutsumi‐Arai, Amy Tran, Yuki Arai, Wanida Ono, Noriaki Ono   +4 more
wiley   +1 more source

AMPK phosphorylates WIP1 to promote DNA repair and radioresistance in cancer cells. [PDF]

Cell Death Dis
Lu M, Dong X, Wu C, Wang G, Wang H, Pan Y, Qin Y, Song Y, Pan H, Liu S, Zhang K, Zhang X, Qu J, Yang Z.   +13 more
europepmc   +1 more source

Porphyromonas gingivalis GroEL accelerates abdominal aortic aneurysm formation by matrix metalloproteinase‐2 SUMOylation in vascular smooth muscle cells: A novel finding for the activation of MMP‐2

Molecular Oral Microbiology, EarlyView.
Abstract Infection is a known cause of abdominal aortic aneurysm (AAA), and matrix metalloproteases‐2 (MMP‐2) secreted by vascular smooth muscle cells (SMCs) plays a key role in the structural disruption of the middle layer of the arteries during AAA progression.
Yi‐Wen Lin, Feng‐Yen Lin, Ze‐Hao Lai, Chien‐Sung Tsai, Yi‐Ting Tsai, Yen‐Sung Huang, Chen‐Wei Liu   +6 more
wiley   +1 more source

SIGNOR 4.0: the 2025 update with focus on phosphorylation data. [PDF]

Nucleic Acids Res
Lo Surdo P, Iannuccelli M, Karis K, Meo E, Omidi P, Tosoni M, Graziosi S, Panni S, Fiorillo MT, Licata L, Sacco F, Gyori BM, Perfetto L.   +12 more
europepmc   +1 more source

EBSn, a Robust Synthetic Reporter for Monitoring Ethylene Responses in Plants

Plant Biotechnology Journal, EarlyView.
ABSTRACT Ethylene is a gaseous plant hormone that controls a wide array of physiologically relevant processes, including plant responses to biotic and abiotic stress, and induces ripening in climacteric fruits. To monitor ethylene in plants, analytical methods, phenotypic assays, gene expression analysis and transcriptional or translational reporters ...
Josefina‐Patricia Fernandez‐Moreno, Mario Fenech, Anna E. Yaschenko, Chengsong Zhao, Matthew Neubauer, Hannah N. Davis, Alex J. Marchi, Raine Concannon, Alexandra Keren‐Keiserman, Moshe Reuveni, Victor Levitsky, Dmitry Oshchepkov, Vladislav Dolgikh, Alexander Goldshmidt, José T. Ascencio‐Ibáñez, Elena Zemlyanskaya, Jose M. Alonso, Anna N. Stepanova   +17 more
wiley   +1 more source