Results 21 to 30 of about 205,153 (377)

IGFBP-3 inhibits Wnt signaling in metastatic melanoma cells. [PDF]

open access: yes, 2016
In previous works, we have shown that insulin-like growth factor-binding protein-3 (IGFBP-3), a tissue and circulating protein able to bind to IGFs, decreases drastically in the blood serum of patients with diffuse metastatic melanoma.
Londei, Paola   +7 more
core   +1 more source

Changes of resting cerebral activities in subacute ischemic stroke patients

open access: yesNeural Regeneration Research, 2015
This study aimed to detect the difference in resting cerebral activities between ischemic stroke patients and healthy participants, define the abnormal site, and provide new evidence for pathological mechanisms, clinical diagnosis, prognosis prediction ...
Ping Wu   +8 more
doaj   +1 more source

Restoring nervous system structure and function using tissue engineered living scaffolds

open access: yesNeural Regeneration Research, 2015
Neural tissue engineering is premised on the integration of engineered living tissue with the host nervous system to directly restore lost function or to augment regenerative capacity following nervous system injury or neurodegenerative disease ...
Laura A Struzyna   +4 more
doaj   +1 more source

The human DEPhOsphorylation Database DEPOD: 2019 update

open access: yesDatabase J. Biol. Databases Curation, 2019
The human Dephosphorylation Database (DEPOD) is a manually curated resource that harbors human phosphatases, their protein and non-protein substrates, dephosphorylation sites and the associated signaling pathways.
N. Damle, M. Köhn
semanticscholar   +1 more source

Thermodynamic and Kinetic Analysis of Sensitivity Amplification in Biological Signal Transduction [PDF]

open access: yes, 2002
Based on a thermodynamic analysis of the kinetic model for the protein phosphorylation-dephosphorylation cycle, we study the ATP (or GTP) energy utilization of this ubiquitous biological signal transduction process.
Bourne   +23 more
core   +5 more sources

Arginine dephosphorylation propels spore germination in bacteria

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance Dormant bacterial spores can survive long periods of time, withstanding extreme conditions, but can rapidly resume a vegetative life form once nutrients become accessible.
B. Zhou   +10 more
semanticscholar   +1 more source

The role of exosomes in peripheral nerve regeneration

open access: yesNeural Regeneration Research, 2015
Peripheral nerve injuries remain problematic to treat, with poor functional recovery commonly observed. Injuries resulting in a nerve gap create specific difficulties for axonal regeneration.
Rosanna C Ching, Paul J Kingham
doaj   +1 more source

The cell surface receptor Tartan is a potential in vivo substrate for the receptor tyrosine phosphatase Ptp52F [PDF]

open access: yes, 2009
Receptor-linked protein-tyrosine phosphatases (RPTPs) are essential regulators of axon guidance and synaptogenesis in Drosophila, but the signaling pathways in which they function are poorly defined.
Bugga, Lakshmi   +2 more
core   +2 more sources

Dephosphorylating eukaryotic RNA polymerase II [PDF]

open access: yesBiochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2016
The phosphorylation state of the C-terminal domain of RNA polymerase II is required for the temporal and spatial recruitment of various factors that mediate transcription and RNA processing throughout the transcriptional cycle. Therefore, changes in CTD phosphorylation by site-specific kinases/phosphatases are critical for the accurate transmission of ...
Joshua E, Mayfield   +2 more
openaire   +2 more sources

Phosphatase-like Activity of Porous Nanorods of CeO2 for the Highly Stabilized Dephosphorylation under Interferences.

open access: yesACS Applied Materials and Interfaces, 2018
Nanoceria with phosphatase-like behavior shows its great potential for many important biological applications through a catalytic dephosphorylation process.
Tianzhu Yao   +3 more
semanticscholar   +1 more source

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