Results 311 to 320 of about 205,153 (377)

14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses

The Journal of Physiology, EarlyView.
Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley   +1 more source

Structural insights into a bacterial terpene cyclase fused with haloacid Dehalogenase-like phosphatase. [PDF]

Chem Sci
Fujiyama K, Takagi H, Vo NNQ, Morita N, Nogawa T, Takahashi S.   +5 more
europepmc   +1 more source

Hypoxia and the cytoskeleton

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

Phylogenetic diversity of light-dependent phosphorylation of Thr78 in Rubisco activase. [PDF]

J Exp Bot
Bhatnagar N, Chung SS, Hodge J, Kim SY, Sands M, Leakey ADB, Ort DR, Burgess SJ.   +7 more
europepmc   +1 more source

Small‐conductance Ca2⁺‐activated K⁺ channels in cardiac excitation–contraction coupling: Bridging mitochondria, sarcolemma and antiarrhythmic therapy

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondrial SK channel enhancement reduces cardiac arrhythmia trigger. Spontaneous sarcoplasmic reticulum (SR) Ca2+ release via hyperactive RyR2s underlies an increased arrhythmia trigger, promoting early and delayed afterdepolarizations during stress. Hyperactive RyR2s causes rise in cytosolic [Ca2+] during diastole. Clearance
Dmitry Terentyev, Alexey V. Glukhov, Vladimir Bogdanov, Aleksei S. Averin, Roland Veress, Bum‐Rak Choi, Shanna Hamilton, Andriy E. Belevych   +7 more
wiley   +1 more source

Mitotic entry is controlled by the plant-specific phosphatase BSL1 and cyclin-dependent kinase B. [PDF]

Nat Plants
Tulin F, Aizezi Y, Reyes AV, Fujieda Y, Grossman A, Xu SL, Onishi M, Assaad FF, Wang ZY.   +8 more
europepmc   +1 more source

PPP2/PP2A-mediated dephosphorylation of LC3B links PINK1-PRKN/Parkin-mediated mitophagy to SCA12 pathogenesis

Ningning Li, Hongyu Hou, Dan Su, Bin Yang, Ruiqing Ni, Guoqiang Ma, Shan Sun, Qilian Ma, Qiang Peng, Siqian Chen, Kin Yip Tam, Hongfeng Wang, Zheng Ying   +12 more
openalex   +2 more sources

Regulation of pyruvate dehydrogenase complex: Dancing to different drums in cancer

International Journal of Cancer, Volume 158, Issue 6, Page 1464-1480, 15 March 2026.
Abstract Mechanisms governing the regulation of pyruvate dehydrogenase complex (PDC) are markedly modified in cancer cells compared to normal cells. PDC activity in normal cells is controlled by the reversible phosphorylation of three serine residues by dedicated kinases and phosphatases.
Mulchand S. Patel, Todd C. Rideout
wiley   +1 more source

Cytoplasmic sequestering of a fungal stress-activated MAPK in response to a host plant phenolic acid. [PDF]

PLoS Pathog
Zuchman R, Koren R, Ziv T, Lupu-Haber Y, Dahan N, Levi O, Horwitz BA.   +6 more
europepmc   +1 more source

Gene Editing and Transformation Strategies for Engineering Drought‐Tolerant Legumes

Legume Science, Volume 8, Issue 1, March 2026.
ABSTRACT Legumes play a vital role in agriculture, nutrition, and the economy, but their production faces significant threats. Among these, drought and its unpredictability will be the most damaging constraint in the coming decades. Enhancing drought tolerance is essential for resilient and sustainable legume cultivation, and genetic engineering ...
Andrea Fernandez‐Gutierrez, Shaun J. Curtin, Juan J. Gutierrez‐Gonzalez   +2 more
wiley   +1 more source