Results 31 to 40 of about 205,153 (377)
Lanthanide-Mediated Dephosphorylation Used for Peptide Cleavage during Solid Phase Peptide Synthesis
Molecules, 2013 Lanthanide(III) ions can accelerate the hydrolysis of phosphomonoesters and phosphodiesters in neutral aqueous solution. In this paper, lanthanide-mediated dephosphorylation has been applied in aqueous media as an orthogonal cleavage condition that can ...
Byunghee Yoo, Mark D. Pagel
doaj +1 more source
Kinase Function of Brassinosteroid Receptor Specified by Two Allosterically Regulated Subdomains
Frontiers in Plant Science, 2022 Plants acquire the ability to adapt to the environment using transmembrane receptor-like kinases (RLKs) to sense the challenges from their surroundings and respond appropriately.
Khawar Ali +10 more
doaj +1 more source
Posttranslational modifications of GLUT4 affect its subcellular localization and translocation [PDF]
, 2013 The facilitative glucose transporter type 4 (GLUT4) is expressed in adipose and muscle and plays a vital role in whole body glucose homeostasis. In the absence of insulin, only ~1% of cellular GLUT4 is present at the plasma membrane, with the vast ...
Bayer +64 more
core +3 more sources
Molecular Plant-Microbe Interactions, 2001 Among plant defense responses to pathogen attack, the release of active oxygen species (AOS), termed the oxidative burst, may affect the attacking pathogen and the host plant cells at the infection site, thereby limiting the spread of the pathogen ...
Tim Xing +3 more
doaj +1 more source
PAK6-mediated phosphorylation of PPP2R2C regulates LRRK2-PP2A complex formation
Frontiers in Molecular Neuroscience, 2023 Mutations in leucine-rich repeat kinase 2 (LRRK2) are a common cause of inherited and sporadic Parkinson’s disease (PD) and previous work suggests that dephosphorylation of LRRK2 at a cluster of heterologous phosphosites is associated to disease. We have
Lucia Iannotta +20 more
doaj +1 more source
PPP1R15A-mediated dephosphorylation of eIF2α is unaffected by Sephin1 or Guanabenz
eLife, 2017 Dephosphorylation of translation initiation factor 2 (eIF2α) terminates signalling in the mammalian integrated stress response (ISR) and has emerged as a promising target for modifying the course of protein misfolding diseases.
Ana Crespillo-Casado +4 more
semanticscholar +1 more source
Neural Regeneration Research, 2015 Apelin-13 inhibits neuronal apoptosis caused by hydrogen peroxide, yet apoptosis following cerebral ischemia-reperfusion injury has rarely been studied. In this study, Apelin-13 (0.1 µg/g) was injected into the lateral ventricle of middle cerebral artery
Xiao-ge Yan +6 more
doaj +1 more source
Advances in regenerative therapies for spinal cord injury: a biomaterials approach
Neural Regeneration Research, 2015 Spinal cord injury results in the permanent loss of function, causing enormous personal, social and economic problems. Even though neural regeneration has been proven to be a natural mechanism, central nervous system repair mechanisms are ineffective due
Magdalini Tsintou +2 more
doaj +1 more source
Infection and Immunity, 2019 Pathogenic Yersinia species deliver Yop effector proteins through a type III secretion system into host cells. Among these effectors, YopE and YopT are Rho-modifying toxins, which function to modulate host cell physiology and evade immune responses ...
Natasha P Medici, M. Rashid, J. Bliska
semanticscholar +1 more source
Neural Regeneration Research, 2015 OBJECTIVE: China is the only country where nerve growth factor is approved for large-scale use as a clinical medicine. More than 10 years ago, in 2003, nerve growth factor injection was listed as a national drug.
Meng Zhao +3 more
doaj +1 more source