Results 41 to 50 of about 205,153 (377)
Advanced Science, 2022 The methyltransferase EZH2 plays an important role in regulating chromatin conformation and gene transcription. Phosphorylation of EZH2 at S21 by AKT kinase suppresses its function.
Lan Zhang +24 more
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Thymidylate Dephosphorylation in Granulocytes.
Experimental Biology and Medicine, 1965 SummaryHuman blood and marrow leukocytes were studied both cytochemically and biochemically for alkaline phosphatase activity. Naturally occurring nucleotides, as well as synthetic compounds, were tested as substrates for leukocytes from varied patients. All substrates reacted similarly with granulocytes from normal subjects. Granulocytes from patients
I D, Stein, J R, Rubini
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A PP2A-B55 recognition signal controls substrate dephosphorylation kinetics during mitotic exit
Journal of Cell Biology, 2016 The phosphatase PP2A-B55 plays an important role in temporal control of mitotic exit; yet, how its substrates are recognized and differentially dephosphorylated is not clear. Using phosphoproteomics and kinetic modeling, Cundell et al.
M. J. Cundell +7 more
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Cell biological mechanisms of activity-dependent synapse to nucleus translocation of CRTC1 in neurons. [PDF]
, 2015 Previous studies have revealed a critical role for CREB-regulated transcriptional coactivator (CRTC1) in regulating neuronal gene expression during learning and memory. CRTC1 localizes to synapses but undergoes activity-dependent nuclear translocation to
Ch'ng, Toh Hean +5 more
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eLife, 2018 Shade avoidance syndrome enables shaded plants to grow and compete effectively against their neighbors. In Arabidopsis, the shade-induced de-phosphorylation of the transcription factor PIF7 (PHYTOCHROME-INTERACTING FACTOR 7) is the key event linking ...
Xu Huang +5 more
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A PxL motif promotes timely cell cycle substrate dephosphorylation by the Cdc14 phosphatase
Nature Structural & Molecular Biology, 2018 The cell division cycle consists of a series of temporally ordered events. Cell cycle kinases and phosphatases provide key regulatory input, but how the correct substrate phosphorylation and dephosphorylation timing is achieved is incompletely understood.
M. Kataria +5 more
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Depletion of Ca2+ from the sarcoplasmic reticulum of cardiac muscle prompts phosphorylation of phospholamban to stimulate store refilling [PDF]
, 1998 Nonmuscle cells have almost ubiquitously evolved a mechanism to detect and prevent Ca(2+) store depletionstore operated calcium entry. No such mechanism has, as yet, been reported in cardiac myocytes.
Bhogal, M.S., Colyer, J.
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Micromachines, 2019 We previously reported on the preparation of supramolecular complexes by the 2:2:2 assembly of a dinuclear Zn2+-cyclen (cyclen = 1,4,7,10-tetraazacyclododecane) complex having a 2,2′-bipyridyl linker equipped with 0~2 long alkyl chains (Zn2L1~Zn2L3)
Yuya Miyazawa +5 more
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Poultry Science, 2023 This study investigated the effects of phytase and monocalcium phosphate supplementation on the dephosphorylation of phytic acid [myo-inositol 1,2,3,4,5,6-hexakis (dihydrogen phosphate); InsP6] in cecectomized laying hens using total excreta collection ...
W. Siegert +3 more
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PKM2 dephosphorylation by Cdc25A promotes the Warburg effect and tumorigenesis
Nature Communications, 2016 Many types of human tumour cells overexpress the dual-specificity phosphatase Cdc25A. Cdc25A dephosphorylates cyclin-dependent kinase and regulates the cell cycle, but other substrates of Cdc25A and their relevant cellular functions have yet to be ...
Ji Liang +8 more
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