Results 231 to 240 of about 296,360 (329)

Auditory Hair Cell Mechanotransduction Channels Dynamically Shape the Mechanical Properties of Their Membrane Environment

open access: yesAdvanced Science, EarlyView.
This work shows, for the first time, that the stereocilia membrane in cochlear hair cells is dynamically regulated by the mechanotransduction channel to impact the membrane mechanical properties. This work provides direct evidence that the opening and closing associated with the MET channel is regulating the membrane viscosity suggesting that the MET ...
Shefin Sam George, Anthony J. Ricci
wiley   +1 more source

Mitochondrial dysfunction mediated by ER-calcium dysregulation in neurons derived from Alzheimer's disease patients. [PDF]

open access: yesActa Neuropathol Commun
Mustaly-Kalimi S   +9 more
europepmc   +1 more source

Utilizing Proteolytic‐Resistant Nano‐Short Peptide Based on Naphthyl Tail‐Anchored to Combat Bacterial Infections

open access: yesAdvanced Science, EarlyView.
Antimicrobial peptides (AMPs) show potential as alternatives to antibiotics for bacterial infections; however, their susceptibility to proteases limits wider application. In this study, N4 nanofibers are constructed by integrating anti‐enzymolysis motif into the self‐assembly system triggered by naphthyl‐anchored.
Xi Yan   +6 more
wiley   +1 more source

In situ cryo-ET visualization of mitochondrial depolarization and mitophagic engulfment. [PDF]

open access: yesProc Natl Acad Sci U S A
Rose K   +7 more
europepmc   +1 more source

Depolarization of central terminals of Group I afferent fibres from muscle

open access: green, 1962
J. C. Eccles   +2 more
openalex   +1 more source

Observations by Lidar of Linear Depolarization Ratios for Hydrometeors [PDF]

open access: hybrid, 1971
R. M. Schotland   +2 more
openalex   +1 more source

Single Mitochondrion Morphology‐Function Relationship Analysis Using Fluorescent Probes and Artificial Intelligence

open access: yesAdvanced Science, EarlyView.
An integrated strategy combining a mitochondria‐targeted fluorescent probe set and an AI framework enables simultaneous analysis of mitochondrial morphology and function at the single organelle level. By fusing multi‐parametric features, machine learning classification accurately distinguishes individual mitochondria under hypoxia‐related conditions ...
Yang Ding   +9 more
wiley   +1 more source

Identification of a Pair of Linear or Cyclic Naturally Inspired Bifunctional Lipopeptide Antibiotics That Overcome Antimicrobial Resistance

open access: yesAdvanced Science, EarlyView.
The underexplored bacterial genus Aquimarina harbors a large biosynthetic potential for discovering new antibiotics. Here, the authors identify a pair of linear or cyclic bifunctional cationic lipopeptide antibiotics, aquicidine L and C4, inspired by the aquicidine gene cluster from Aquimarina.
Lei Li, Yiwen Zhou, Yuzhu Wu
wiley   +1 more source

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