Results 91 to 100 of about 2,320,726 (240)

Functions and Therapeutic Potentials of Long Noncoding RNA in Skeletal Muscle Atrophy and Dystrophy

Journal of Cachexia, Sarcopenia and Muscle
Skeletal muscle is the most abundant tissue in the human body and is responsible for movement, metabolism, energy production and longevity. Muscle atrophy is a frequent complication of several diseases and occurs when protein degradation exceeds protein ...
Yidi Zhang, Teng Wang, Ziang Wang, Xin'e Shi, Jianjun Jin   +4 more
doaj   +1 more source

Kinetics and Intermediate Phases in Epitaxial Growth of Fe3O4 Films from Deposition and Thermal Reduction

, 2016
We have studied the growth of Fe3O4 (111) epitaxial films on Al2O3 (001) substrates using a pulsed laser deposition / thermal reduction cycle using an {\alpha}-Fe2O3 target.
Xu, Xiaoshan, Yang, Sen, Yang, Zhimao, Zhang, Xiaozhe   +3 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

THE DISTRIBUTION OF FILLER MATERIAL ON BASE METALS DURING BRAZING OF ALUMINUM ALLOYS [PDF]

Fiabilitate şi Durabilitate, 2013
Since aluminum brazing technology is relatively new compared to other permanent joiningtechnologies, this technological process needs a scientific approach.One of the specific parameters of this type of technological processes is the distribution of ...
Andrei DIMITRESCU
doaj  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Neutron radiation induced transmutation of boron to lithium in aluminum-boron nitride composite

Materials Today Advances
Lightweight materials are essential for applications in harsh environments, such as space explorations, where materials must exhibit exceptional durability and resistance to radiation damage for both humans and equipment.
Sohail M.A.K. Mohammed, Zehao Li, Kazue Orikasa, Arun Devaraj, David Garcia, R. Sarvesha, Anil Lama, Mayur Pole, Cheol Park, Sang-Hyon Chu, Ken Ross, Arvind Agarwal   +11 more
doaj   +1 more source

Formation of hydroxyapatite coatings with addition of chitosan from aqueous solutions by thermal substrate method [PDF]

Журнал інженерних наук, 2017
The aim of this investigation was obtaining of biocompatible coatings for medical implants based on biopolymer chitosan and hydroxyapatite, which is the main mineral component of bone tissue. Coatings were obtained by thermal substrate method, because it
Yanovska G. O., Bolshanina S. B., Kuznetsov V. M.   +2 more
doaj  

Using ultra-thin parylene films as an organic gate insulator in nanowire field-effect transistors

, 2018
We report the development of nanowire field-effect transistors featuring an ultra-thin parylene film as a polymer gate insulator. The room temperature, gas-phase deposition of parylene is an attractive alternative to oxide insulators prepared at high ...
Carrad, D.J.,, Cochrane, J.W.,, Gluschke, J.G.,, Lehmann, Sebastian,, Lund University., Lund University., Lyttleton, Roman,, Micholich, A.P.,, Samuelson, Lars,, Seidl, J.,   +9 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source