Results 91 to 100 of about 1,322,802 (314)
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Functions and Therapeutic Potentials of Long Noncoding RNA in Skeletal Muscle Atrophy and Dystrophy
Journal of Cachexia, Sarcopenia and MuscleSkeletal muscle is the most abundant tissue in the human body and is responsible for movement, metabolism, energy production and longevity. Muscle atrophy is a frequent complication of several diseases and occurs when protein degradation exceeds protein ...
Yidi Zhang +4 more
doaj +1 more source
A Study on Dust Dry Deposition: Wind-tunnel Experiment and Improved Parameterization
, 2013 Dust deposition is a key component of the dust cycle in the Earth system. The lack of understanding for the mechanisms of dust deposition has been a major bottle neck to the development of the dust-related research field.
Zhang, Jie
core
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
National Atmospheric Deposition Program 2003 Annual Summary
, 2003 is peer reviewedSubmitted by Susan Braxton (braxton@illinois.edu) on 2011-10-21T01:22:27Z No. of bitstreams: 1 2003as.pdf: 4347873 bytes, checksum: cee7d046da768ca5fc97c93f07b97012 (MD5)Made available in DSpace on 2011-10-21T01:22:27Z (GMT). No.
National Atmospheric Deposition Program
core
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
THE DISTRIBUTION OF FILLER MATERIAL ON BASE METALS DURING BRAZING OF ALUMINUM ALLOYS [PDF]
Fiabilitate şi Durabilitate, 2013 Since aluminum brazing technology is relatively new compared to other permanent joiningtechnologies, this technological process needs a scientific approach.One of the specific parameters of this type of technological processes is the distribution of ...
Andrei DIMITRESCU
doaj
FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
Formation of hydroxyapatite coatings with addition of chitosan from aqueous solutions by thermal substrate method [PDF]
Журнал інженерних наук, 2017 The aim of this investigation was obtaining of biocompatible coatings for medical implants based on biopolymer chitosan and hydroxyapatite, which is the main mineral component of bone tissue. Coatings were obtained by thermal substrate method, because it
Yanovska G. O. +2 more
doaj