Results 21 to 30 of about 807,453 (268)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Leptin Promotes White Adipocyte Browning by Inhibiting the Hh Signaling Pathway

Cells, 2019
Leptin is an important secretory protein that regulates the body’s intake and energy consumption, and the functions of the Hh signaling pathway related to white adipocyte browning are controversial. It has been reported that leptin plays a critical
Jie Wang, Jing Ge, Haigang Cao, Xiaoyu Zhang, Yuan Guo, Xiao Li, Bo Xia, Gongshe Yang, Xin’e Shi   +8 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

In-situ observation of twinning and grain rotation assisted deformation in wire-arc direct energy deposited (WDED) single phase titanium

Journal of Materials Research and Technology
Additive manufacturing of metals often results in microstructural inhomogeneities, leading to the simultaneous or sequential activation of multiple deformation mechanisms.
Blanca Palacios, Sohail M.A.K. Mohammed, Tanaji Paul, Brandon Aguiar, Sean Langan, Arvind Agarwal   +5 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Widespread impacts to precipitation of the East Palestine Ohio train accident

Environmental Research Letters
On 3 February 2023, a Norfolk Southern train derailment occurred in East Palestine, Ohio. The accident and subsequent fire resulted in the emissions of large amounts of hazardous compounds to the ambient atmosphere over many days.
David A Gay, Katelan Blaydes, James J Schauer, Martin Shafer   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Integrating parental genomes to reduce reference bias and identify intramuscular fat genes in Qinchuan Black pigs

Journal of Animal Science and Biotechnology
Background Traditional genomic analysis relies on a single reference genome, which struggles to effectively characterize the genetic diversity among populations. This is due to the substantial genetic differences between the genome of the studied species
Guangquan Lv, Peiyu Yang, Ao Guo, Minghao Cao, Dong Li, Zhe Liu, Mingyu Wang, Jingchun Sun, Rongrong Ding, Taiyong Yu   +9 more
doaj   +1 more source

Influences of welding speed on microstructure and mechanical properties of friction stir welded Al–Mg alloy with high Mg content

Materials Research Express, 2020
In this work, the influences of welding speed on microstructure and mechanical properties in friction stir welding (FSW) of the hot-rolled Al-9.2Mg-0.8Mn-0.2Zr-0.15Ti alloy plates has been investigated.
Yingli Li, Hongge Yan, Jihua Chen, Weijun Xia, Bin Su, Tian Ding, Xinyu Li   +6 more
doaj   +1 more source

Atmospheric Conditions for Uplift and Dust Transport in the Latitudinal 10° North–20° North Band in Africa

Atmosphere, 2022
Desert aerosols suspended in the atmosphere are a very marked fact in West Africa with estimates of 400 to 1000 million tons produced annually and concentrations exceeding 50 µg·m³ in Burkina.
Abdoulaye Bouya Diop, Malick Wade, Abdoulaye Sy, Abdoul Karim Mbodji, Abdou Karim Farota, El hadji Deme, Babacar Niang, Bouya Diop, Amadou Thierno Gaye, Aboubakary Diakhaby   +9 more
doaj   +1 more source