Results 31 to 40 of about 1,322,802 (314)
Journal of NanobiotechnologyBackground Skeletal muscle lipid deposition is a key manifestation of obesity, often accompanied by decreased exercise capacity and muscle atrophy. Skeletal muscle as the largest organ in the body, makes it challenges for designing targeted drug delivery
Yingqian Wang +8 more
doaj +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Development of an original model for the synthesis of silicon nanodots by Low Pressure Chemical Vapor Deposition [PDF]
, 2008 Using the Computational Fluid Dynamics code Fluent, a simulation model of an industrial Low Pressure Chemical Vapor Deposition reactor has been developed for the synthesis of silicon nanodots from silane SiH4 on silicon dioxide SiO2 substrates.
Billon, Thierry +4 more
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Leptin Promotes White Adipocyte Browning by Inhibiting the Hh Signaling Pathway
Cells, 2019 Leptin is an important secretory protein that regulates the body’s intake and energy consumption, and the functions of the Hh signaling pathway related to white adipocyte browning are controversial. It has been reported that leptin plays a critical
Jie Wang +8 more
doaj +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Journal of Materials Research and TechnologyAdditive manufacturing of metals often results in microstructural inhomogeneities, leading to the simultaneous or sequential activation of multiple deformation mechanisms.
Blanca Palacios +5 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Widespread impacts to precipitation of the East Palestine Ohio train accident
Environmental Research LettersOn 3 February 2023, a Norfolk Southern train derailment occurred in East Palestine, Ohio. The accident and subsequent fire resulted in the emissions of large amounts of hazardous compounds to the ambient atmosphere over many days.
David A Gay +3 more
doaj +1 more source
Atmosphere, 2022 Desert aerosols suspended in the atmosphere are a very marked fact in West Africa with estimates of 400 to 1000 million tons produced annually and concentrations exceeding 50 µg·m³ in Burkina.
Abdoulaye Bouya Diop +9 more
doaj +1 more source