Results 61 to 70 of about 1,322,802 (314)

Effects of Interactions between Feeding Patterns and the Gut Microbiota on Pig Reproductive Performance

open access: yesAnimals
The feeding mode is an important factor affecting the reproductive performance of pigs. The composition and expression of the intestinal microbiota are closely related to the physiological and biochemical indicators of animals.
Mingyu Wang   +7 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

The hybridization analysis of pedigree: whole-genome re-sequencing reveals genomics characterization and genetic basis of growth trait of Qinchuan black pigs

open access: yesBMC Genomics
Background Understanding the genetic basis of hybridization trait between Chinese indigenous pig and their commercial relatives may contribute to germplasm innovation. The Qinchuan black (QCB) pig is a new composite breed under development generated from
Minghao Cao   +7 more
doaj   +1 more source

Evaporative deposition patterns: Spatial dimensions of the deposit [PDF]

open access: yesPhysical Review E, 2005
A model accounting for the finite spatial dimensions of the deposit patterns in evaporating sessile drops of a colloidal solution on a plane substrate is proposed. The model is based on the assumption that the solute particles occupy finite volume and hence these dimensions are of steric origin. Within this model, the geometrical characteristics of the
openaire   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Modeling the Transport and Retention of Nanoparticles in a Single Partially Saturated Pore in Soil

open access: yesWater Resources Research, 2023
Pore‐network models are powerful tools for studying particle transport in complex porous media, and investigating the role of interfaces in their fate.
J. Jayaraj   +2 more
doaj   +1 more source

The Effect of Deposition Temperature of TiN Thin Film Deposition Using Thermal Atomic Layer Deposition

open access: yes, 2023
In this study, the effect of deposition temperature of TiN thin films deposited using the thermal atomic layer deposition (ALD) method was investigated.
Yoo-Seong Kim   +3 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Numerical Simulation Analysis of the Temperature Field of Molten Salt Linear Fresnel Collector

open access: yesEnergies
A complex operating environment and high operating temperature lead to the uneven temperature field distribution of key components of the molten salt Linear Fresnel collector in a way that compromises the collector’s safety and stability.
Linggang Kong   +4 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

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