Results 101 to 110 of about 4,595 (134)

On the way to deprescribing levothyroxine in subclinical hypothyroidism in general practice – the patients’ perspective of enablers and barriers

European Journal of General Practice
Background Recent studies indicate that the synthetic thyroid hormone levothyroxine (LTX) in many cases has no beneficial effects on patients with subclinical hypothyroidism. Still, prescriptions are increasing worldwide.
M. Rennert, A. K. Geier, L. Christ, S. Hager, S. Scheibe, A. Rettich, J. Schübel, T. Deutsch, M. Bleckwenn, K. Voigt   +9 more
doaj   +1 more source

Associations Between Multimorbidity, Polypharmacy and Oral Conditions in Older Adults: A Systematic Review and Meta‐Analysis

Gerodontology, Volume 43, Issue 3, Page 403-419, September 2026.
ABSTRACT Objective This systematic review and meta‐analysis evaluated the relationship between multimorbidity and polypharmacy on the oral health in older adults (aged 75 years or older). The PECO focus question set for this study was, ‘What is the occurrence, association and impact of multimorbidity and polypharmacy on the oral conditions and its ...
Kittipit Srisanoi, Sabrina Maniewicz, Claudio Rodrigues Leles, Gerry McKenna, Frauke Müller, Murali Srinivasan   +5 more
wiley   +1 more source

Instruments for assessing healthcare professionals’ knowledge, attitudes and practices regarding deprescribing: a scoping review protocol

BMJ Open
Objective To map instruments for assessing healthcare professionals’ knowledge, attitudes and practices regarding deprescribing.Introduction Deprescribing is essential for improving patient outcomes by managing polypharmacy, reducing fall risks and ...
Luciane Cruz Lopes, Jardel Corrêa de Oliveira, Luis Phillipe Nagem Lopes, Mariana Del Grossi Moura, Ana Carolina Figueiredo Modesto, Laís Lessa Neiva Pantuzza   +5 more
doaj   +1 more source

Geriatric Models of Surgical Care: A Scoping Review

Journal of Advanced Nursing, Volume 82, Issue 9, Page 8425-8440, September 2026.
ABSTRACT Aim To synthesise literature on hospital‐based geriatric models of care for older adults undergoing surgery, examining structures, team composition, governance and nursing contributions. Design Scoping review. Methods Following JBI methodology, two reviewers independently screened articles against eligibility criteria (Population: adults ≥ 65 ...
Sarah Hughes, Ut Bui, Clint Douglas, Andrea Taylor   +3 more
wiley   +1 more source

Barriers to and facilitators of deprescribing for older people in secondary care in Saudi Arabia: a qualitative study using a theory-based approach

BMC Geriatrics
Background In Saudi Arabia, over 55% of older people are exposed to potentially inappropriate medications. Deprescribing, a structured process to identify and discontinue unnecessary or harmful medications under medical supervision, by healthcare ...
Turkeah M. Alenzy, Heather E. Barry, Saad A. Alkahtani, Carole Parsons   +3 more
doaj   +1 more source

Guideline for Medication Management of Distressing Symptoms in Older Patients Receiving End‐of‐Life Palliative Care

Journal of Evidence-Based Medicine, Volume 19, Issue 3, September 2026.
ABSTRACT Older patients receiving end‐of‐life palliative care often present with multiple geriatric syndromes, frailty, and comorbid symptom burden, resulting in a high risk of medication‐related harm. This guideline focuses on pharmacological management of distressing symptoms in older patients receiving end‐of‐life or hospice‐oriented palliative care,
Daiping Li, Yanwu Yang, Yan Zhang, Jirong Yue, Birong Dong, Meiling Ge, National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University   +7 more
wiley   +1 more source

Aspirin Deprescribing Interventions for Primary Prevention: A Systematic Review and Proposed Guidance for Deprescribing.

Recent literature indicates that the benefits of aspirin use for primary prevention of atherosclerotic cardiovascular disease (ASCVD) may be equivocal to the risk.
Mohammad, Insaf, Martirosov, Amber Lanae, Berlie, Helen, Lobkovich, Alison, Ferrari, Hannah, Lipari, Melissa, Garwood, Candice   +6 more
core   +2 more sources

Substitution Patterns After Discontinuation of CNS‐Active Medications in Older Adults in Primary Care

Journal of the American Geriatrics Society, Volume 74, Issue 9, Page 2704-2709, September 2026.
ABSTRACT Background Little is known about substitution of alternative medications in the context of deprescribing. The objectives were to: (1) determine the frequency of medication substitutions among those who discontinued a central nervous system (CNS)‐active medication, and (2) characterize substitutions as potentially inappropriate (as per the 2023
Shelly L. Gray, Annalisa V. Piccorelli, Laura A. Hart, Andrea J. Cook, Brian D. Williamson, Benjamin H. Balderson, Elizabeth A. Phelan   +6 more
wiley   +1 more source

Awareness, perspectives and practices of antibiotics deprescribing among physicians in Jordan: a cross-sectional study

Journal of Pharmaceutical Policy and Practice
Background: Antibiotics have significantly reduced mortality and improved outcomes across various medical fields; however, the rise of antibiotic resistance poses a major challenge, causing millions of deaths annually.
Rana Abu-Farha, Lobna Gharaibeh, Karem H. Alzoubi, Rawand Nazal, Mohammed Zawiah, Ammena Y. Binsaleh, Sireen Abdul Rahim Shilbayeh   +6 more
doaj   +1 more source

Polypharmacy and Deprescribing in Older Adults [PDF]

Older adults commonly end up on many medications. Deprescribing is an important part of individualizing care for older adults. It is an opportunity to discuss treatment options and revisit medications that may not have been reassessed in many years.
McDonald, Emily G, Thompson, Wade
core   +1 more source