Results 91 to 100 of about 4,595 (134)

Technology‐Driven Decision Support for Opioid Tapering: A Scoping Review

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 3, September 2026.
ABSTRACT Background General practitioners manage most opioid tapering. This process requires time‐consuming, individualised planning accounting for patient preferences, dose options and costs. Consequently, clinicians need tools to support tapering.
Laurits Valberg Hemmingsen, Lærke Karner Overgaard, Uffe Kock Wiil, Daniel Pilsgaard Henriksen   +3 more
wiley   +1 more source

Deprescribing oral antidiabetics in elderly patients: Do electronic leaflets across the world address it?

Exploratory Research in Clinical and Social Pharmacy
Diabetes caused 6.7 million deaths in 2021, equating to one death every five seconds, with its global financial burden projected to rise from $1.32 trillion in 2015 to $2.12 trillion by 2030.
Kitete Tunda Bunnel, Silvio José Elisei Carvalho, Jr, Mariana Linhares Pereira, Renê Oliveira Couto, André Oliveira Baldoni   +4 more
doaj   +1 more source

Exploring the need for a clinical decision support system for deprescribing - A qualitative interview study

Exploratory Research in Clinical and Social Pharmacy
Background: Deprescribing (i.e., the process of discontinuing an inappropriate medication) requires time, knowledge, and care, but there is a lack of education, support, and guidelines for this important clinical task. A clinical decision support system (
Aryoutha Asmar Talani, Tora Hammar, Ylva Böttiger   +2 more
doaj   +1 more source

The Feasibility and Acceptability of a Collaborative Deprescribing Intervention to Reduce Anticholinergic Burden Among Hospitalised Older Patients

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 3, September 2026.
ABSTRACT Introduction 37%–48% of older patients receive anticholinergic medicines, increasing the risk for falls, delirium, dementia and death. Hospital admission may provide an opportunity for deprescribing to improve outcomes. This study evaluated the feasibility and acceptability of a digital tool to identify anticholinergic medicines and support ...
Kinda Ibrahim, Eloise Radcliffe, Edward Hewertson, Andrew Bates, Andy Fox, Emily Smith, Cathrine Mckenzie, Liam Jones, Sara Mckelvie, Ngianga Ii Kandala, Sara McCloskey, Tracey Sach, Stephen Lim   +12 more
wiley   +1 more source

Deprescribing potential of commonly used medications among community-dwelling older adults: insights from a pharmacist’s geriatric assessment

Scientific Reports
Pharmacist’s geriatric assessment can provide valuable insights into potential deprescribing targets, while including important information on various health-related domains.
Iva Bužančić, Margita Držaić, Ingrid Kummer, Maja Ortner Hadžiabdić, Jovana Brkić, Daniela Fialová   +5 more
doaj   +1 more source

Deprescription of Psychotropics in Children and Adolescents: Systematic Review of Guidelines and Development of a Deprescribing Algorithm

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 3, September 2026.
ABSTRACT Background Psychotropics are increasingly prescribed in paediatrics despite limited evidence regarding their benefits and effectiveness. Although deprescribing approaches are established in adults, structured paediatric strategies remain poorly defined.
Paul‐Benoît Fargier, Mark Horowitz, Rodolphe Charles, Valérie Rousselon, Erik Fakra, Marie‐Noëlle Beyens, Marie‐Laure Laroche   +6 more
wiley   +1 more source

Practical approaches to deprescribing in general practice

Background:Polypharmacy is common in older people and is associated with a higher risk of adverse drug events, hospitalisation and diminished quality of life. Deprescribing, defined as the planned and supervised reduction or discontinuation of medicines,
Doust, Jenny, Quek, Hui Wen, Weir, Kristie Rebecca, Graham, Alice, Morgan, Mark A; id_orcid   +4 more
core   +1 more source

Deprescribing within English care homes: guidance and recommendations from the STOPPING project

Health Literacy and Communication Open
Background Care home residents often experience polypharmacy. Deprescribing, or the reduction or stopping of prescription medicines that may no longer be providing benefit, is generally safe but it is unknown how to make it work well in care homes.Aim ...
Krystal Warmoth, Alex Aylward, Jo Day
doaj   +1 more source

“Put Me in, Coach”: A Discussion of Deprescribing Roles, Responsibilities, and Motivations Based on a Qualitative Study with Healthcare Professional Students

Pharmacy
As the US population ages, the number of prescriptions managed by patients and healthcare teams is increasing. Thus, discontinuing or reducing medications that are considered to pose more risks than benefits can be achieved through deprescribing. Despite
Devin Scott, Amy Hall, Rachel Barenie, Crystal Walker, Muneeza Khan, Paul Koltnow, William R. Callahan, Alina Cernasev   +7 more
doaj   +1 more source

A SHAP‐Informed Formal Feature Attribution Framework for Drug–Drug Interaction Risk in Large‐Scale Claims Data

Clinical and Translational Science, Volume 19, Issue 9, September 2026.
ABSTRACT Pairwise drug–drug interaction databases flag co‐prescribed pairs, but they under‐weight multi‐drug combinations that drive adverse drug events in older adults. We studied that gap in Virginia All‐Payer Claims Database records (2016–2019) for adults aged 65–114 years with non‐opioid emergency department visits (n = 1182 cases; 16,105 matched ...
R. Jerome Dixon, Elvin T. Price
wiley   +1 more source