Results 31 to 40 of about 4,595 (134)

Antidepressant Prescribing Trends for Adults With and Without Autism in the United Kingdom From 1997 to 2023: A Population‐Based Cohort Study Using Clinical Practice Research Datalink Aurum

Autism Research, EarlyView.
ABSTRACT Antidepressant prescribing and autism diagnoses have increased in recent years. We aimed to describe and compare trends in antidepressant prescribing, indications, doses and durations in autistic and non‐autistic males and females in the United Kingdom (UK) from 1997 to 2023.
Aws Sadik, Golam M. Khandaker, Antonio F. Pardiñas, Michael Lundberg, Brian K. Lee, Cecilia Magnusson, Dheeraj Rai, Paul Madley‐Dowd   +7 more
wiley   +1 more source

Older Adult Attitudes toward Deprescribing Statins in Primary Cardiovascular Prevention Versus General Medications. [PDF]

Background: There is little evidence for statins for primary cardiovascular prevention in older adults. Consequently, it is important to assess patient attitudes toward the use of statins, which might differ from attitudes toward other medications.
Brunner, Laureline, Rodondi, Nicolas, Spinewine, Anne, Aubert, Carole Elodie, Bardoczi, Julia Bianca   +4 more
core   +2 more sources

Deprescribing guidelines:An international symposium on development, implementation, research and health professional education [PDF]

, 2019
Deprescribing is a clinically important and feasible innovation that ensures medication efficacy, reduces harms, and mitigates polypharmacy. It involves reducing doses or stopping medications that are not useful, no longer needed, or which may be causing
McCarthy, Lisa, Dolovich, L., Raman Wilms, L., Moriarty, Frank, Conklin, J., Irving, Hannah, Farrell, B., McCarthy, L., Reeve, E., Conklin, James, Thompson, Wade, Farrell, Barbara, Moriarty, F., Reeve, Emily, Pottie, Kevin, Thompson, W., Irving, H., Maclure, M., Maclure, Malcolm, Pottie, K., Dolovich, Lisa, Raman-Wilms, Lalitha   +21 more
core   +1 more source

Clinical relevance of pharmacogenomic information for improving prescribing practices in acutely admitted older medical patients

British Journal of Clinical Pharmacology, EarlyView.
Aims Safe prescribing and effective medication review during acute hospitalization depends on accurate information about liver and kidney function because these organs are responsible for the elimination of most medications. While estimates for kidney function are widely used, comparable markers of hepatic drug‐metabolizing capacity are not routinely ...
Louise Westberg Strejby Christensen, Anne Kirstine Boas, Emilie Clausen, Nicoline Elers Koch, Anne Byriel Walls, Lotte Stig Nørgaard, Michael Asger Andersen, Anissa Aharaz, Rikke Lundsgaard Nielsen, Olivia Bornæs, Juliette Tavenier, Baker Nawfal Jawad, Helle Gybel Juul‐Larsen, Esben Iversen, Ove Andersen, Lona Louring Christrup, Kim Peder Dalhoff, Morten Baltzer Houlind   +17 more
wiley   +1 more source

Improving the feasibility of deprescribing proton pump inhibitors: GPs’ insights on barriers, facilitators, and strategies

Frontiers in Pharmacology
IntroductionThe prevalent overprescribing of proton pump inhibitors (PPIs) poses health risks from prolonged use. GPs play a key role in initiating deprescribing PPIs, so understanding their decision-making factors and strategies to improve feasibility ...
Nuša Japelj, Lea Knez, Lea Knez, Davorina Petek, Nejc Horvat   +4 more
doaj   +1 more source

The deprescribing rainbow: a conceptual framework highlighting the importance of patient context when stopping medication in older people

BMC Geriatrics, 2018
The area of “deprescribing” has rapidly expanded in recent years as a positive intervention to reduce inappropriate polypharmacy and improve health outcomes for (older) people with multimorbidity. While our understanding of deprescribing as a process has
Adam Todd, Jesse Jansen, Jim Colvin, Andrew J. McLachlan   +3 more
doaj   +1 more source

Benzodiazepines use in primary care England: Prescribing patterns and adverse consequences

British Journal of Clinical Pharmacology, EarlyView.
Aims Benzodiazepines (BZDs) are commonly prescribed for anxiety and insomnia but carry risks such as dependence, adverse drug reactions (ADRs) and mortality. Despite deprescribing efforts, the influence of recent prescribing trends, COVID‐19 and adverse outcomes on prescribing patterns in England remains uncertain.
Alvina Chaudhry, Muhammad Umair Khan, Barbara Conway, Syed Shahzad Hasan   +3 more
wiley   +1 more source

Antipsychotics deprescribing in schizophrenia: trends and associated characteristics in Belgium and Québec

, 2022
Background : Antipsychotic polypharmacy (APP) is common worldwide in schizophrenia, while switch to antipsychotic monotherapy reduces adverse effects. Canada has been the leader in deprescribing policies in the last decades.
Elens, Laure, de Timary, Philippe, Dalleur, Olivia, International Conference on Deprescribing ICOD, Lagreula, Juliette   +4 more
core  

Towards appropriate guidance for the ethical challenges of environmentally sustainable prescribing

British Journal of Clinical Pharmacology, EarlyView.
The environmental impact of medicines poses a significant threat to planetary and public health, making it essential to integrate environmental sustainability into prescribing practices. While the most effective measures to reduce environmental impact, such as reducing unnecessary prescriptions and medication waste, are consistent with appropriate ...
Joost D. Piët, Steven R. Kraaijeveld, Erik M. Donker, Milan C. Richir, Caroline T. A. Moermond, Amy Booth, SanYuMay Tun, Thijs H. Oude Munnink, Patricia M. L. A. van den Bemt, Lorena Dima, Ben J. A. Janssen, Mathilde Jalving, Tomás Mauro van Emden, Fabrizio de Ponti, Robert Likic, João Costa, Marc Labriffe, Charlotte L. Bekker, Carlotta Lunghi, Elisabetta Poluzzi, Michiel A. van Agtmael, Yolande Voskes, Jelle Tichelaar   +22 more
wiley   +1 more source

Pharmacotherapy and deprescribing

, 2019
This chapter discusses the concept and practice of deprescribing. Deprescribing has been defined as the process of identifying and withdrawing an inappropriate medication, supervised by a health-care professional.
Reeve, Emily, Hilmer, Sarah N., Scott, Ian   +2 more
core   +1 more source