Results 41 to 50 of about 4,595 (134)

Identifying barriers and facilitators to deprescribing benzodiazepines and sedative hypnotics in the hospital setting using the Theoretical Domains Framework and the Capability, Opportunity, Motivation and Behaviour (COM-B) Model: a qualitative study

BMJ Open, 2023
Objectives Geriatric guidelines strongly recommend avoiding benzodiazepines and non-benzodiazepine sedative hypnotics in older adults. Hospitalisation may provide an important opportunity to begin the process of deprescribing these medications ...
Jeffrey L Schnipper, Joshua M Pevnick, Teryl K Nuckols, Michelle S Keller, Johan Carrascoza-Bolanos, Kathleen Breda, Linda Y Kim, Korey A Kennelty, Donna W Leang, Logan T Murry   +9 more
doaj   +1 more source

Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

ESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi, Maria Giulia Bellicini, Marianna Adamo, Andrea Pilotto, Marco Metra, Alessandro Padovani, Riccardo Proietti   +6 more
wiley   +1 more source

Who has the guts to deprescribe proton pump inhibitors? A pharmacist‐led intervention in a long‐term care facility setting

Aging Medicine, 2019
Objective Long‐term use of proton pump inhibitors (PPIs) has been associated with an increased risk of harm. There are few studies evaluating pharmacist‐led PPI deprescribing interventions within a long‐term care facility setting.
Rachel Tandun, Carolyn Bubbar, Aaron M. Tejani   +2 more
doaj   +1 more source

Perspectives of health professionals towards deprescribing practice in Asian nursing homes: a qualitative interview study

BMJ Open, 2019
Objective To examine the determinants of deprescribing among health professionals in nursing homes, focusing on knowledge, practice and attitude.Design This was a qualitative study comprising semi-structured face-to-face interviews guided by 10 open ...
Shaun Wen Huey Lee, Chong-Han Kua, Vivienne SL Mak   +2 more
doaj   +1 more source

Outcomes of pharmacist‐led deprescribing interventions in older adults living in long‐term care facilities: a scoping review

Journal of Pharmacy Practice and Research, EarlyView.
Abstract Background An increase in the ageing population across long‐term care facilities (LTCFs) has led to an increased risk of polypharmacy. Pharmacist‐led deprescribing (PLD) can reduce these risks but there are limitations to its widespread uptake.
Sefunmi Odetola, Eileen Willis, Katrina Lane‐Krebs, Ashlyn Sahay   +3 more
wiley   +1 more source

A Cross-Sectional Analysis of Deprescribing Curricular Exposure, Attitudes, and Preparedness Among Undergraduate Pharmacy Students in Saudi Arabia

Pharmacy
Objectives: This study aimed to assess pharmacy students’ curricular exposure to deprescribing, their attitudes and preparedness to perform core deprescribing steps, and their understanding of interprofessional roles in the deprescribing process. Methods:
Lina Altayeb, Hend Talkhan, Rayah Asiri, Rawan Aloqran, Arwa Al Saeed, Khalid Orayj   +5 more
doaj   +1 more source

A comparative analysis of the prevalence of medicine classes and polypharmacy between community‐dwelling and residential aged care populations in Western Australia

Journal of Pharmacy Practice and Research, EarlyView.
Abstract Background Polypharmacy is a global issue, particularly among residential aged care home (RACH) residents with multimorbidity and complex care needs. However, population‐level evidence on longitudinal trends and comparisons with community‐dwelling (CD) older adults remains limited.
David Lim, Ninh Ha, David Youens, Rachael Moorin, Andrew Stafford   +4 more
wiley   +1 more source

Deprescribing proton pump inhibitors in long-term care: Outcomes of a pharmacist-led initiative

Exploratory Research in Clinical and Social Pharmacy
Background: Proton pump inhibitors (PPIs) are frequently continued without clear indication in long-term care (LTC) settings. Evidence-based deprescribing strategies may reduce unnecessary exposure, but real-world data from Middle Eastern LTC facilities ...
Amira Muhana, Rizah Anwar Assadi, Amir Mahdi, Alaa Fathy, Martin Farina, Mariam Jihad Diab   +5 more
doaj   +1 more source

Association Between Proton‐Pump Inhibitors and Muscle Strength in Older Adults: A Population‐Based Analysis

Journal of Digestive Diseases, EarlyView.
In this population‐based study of 616 older adults, we analyzed the associations of proton‐pump inhibitor (PPI) use with handgrip strength, 4‐m walking performance, and armchair push–pull performance. After adjusted for age, sex, body mass index, and comorbidity burden using the Charlson Comorbidity Index (CCI), only the association with armchair push ...
Jaakko Ollila, Konsta Teppo, Kimmo Salminen, Adriana Lääti, Jenni Vire, Matti Viitanen, Ville Langén   +6 more
wiley   +1 more source

Lessons learned from Canadian family physicians deprescribing medications in older adults – a five-year retrospective review of medico-legal cases

BMC Geriatrics
Background Medication-related safety incidents are more common in older adults than in younger populations. Medication review and optimization, including deprescribing, are essential components of strategies to reduce medication-related harm ...
Jeffrey D Smith, Cheryl A Sadowski, Justin Y Lee, Catherine Bernard, Genevieve M Casey, Katherine E Larivière, PJ Finestone, Cathy Zhang, Gary E Garber   +8 more
doaj   +1 more source