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Suicide‐specific mortality among patients with treatment‐resistant major depressive disorder, major depressive disorder with prior suicidal ideation or suicide attempts, or major depressive disorder alone [PDF]
Brain and Behavior, 2023 Background The impact of treatment‐resistant depression (TRD) or prior suicidal ideation/suicide attempt (SI/SA) on mortality by suicide among patients with major depressive disorder (MDD) is not well known. This retrospective, observational, descriptive
David M. Kern +7 more
doaj +2 more sources
South African Journal of Psychiatry, 2013 The treatment guideline draws on several international guidelines: (i)Practice Guidelines of the American Psychiatric Association (APA)for the Treatment of Patients with Major Depressive Disorder, SecondEdition;[1](ii) Clinical Guidelines for the ...
G Grobler
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Major depressive disorder [PDF]
, 2007 Depression in its various forms is a commonly seen disorder in general practice. Indeed, over 90% of patients suffering from depression are seen, diagnosed and treated in primal) care.
Bonello, Arlene
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Bipolar and major depressive disorders: associations with serum zonulin levels and rs2070937 polymorphism [PDF]
BMC PsychiatryBackground The underlying pathophysiology of bipolar disorder and major depressive disorder is not fully understood. Inflammation is increasingly recognized as a contributing factor. The gut plays a central role in this process.
Ozgur Baykan +3 more
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Major depressive disorder [PDF]
Nature Reviews Disease Primers, 2016 Major depressive disorder (MDD) is a debilitating disease that is characterized by depressed mood, diminished interests, impaired cognitive function and vegetative symptoms, such as disturbed sleep or appetite. MDD occurs about twice as often in women than it does in men and affects one in six adults in their lifetime.
Otte, Christian +7 more
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Perfectionism in Major Depressive Disorder [PDF]
Psikiyatride Güncel Yaklaşımlar, 2020 Perfectionism is individuals setting hard-to-reach goals for themselves or others and striving to achieve them. People have difficulties in their lives because of their perfectionist thinking.
Gülen Say
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Major Depressive Disorder [PDF]
Neuron, 2000 In summary, MDD is a highly prevalent major medical whose pathophysiology is still poorly understood. MDD is often recurrent or chronic, and evidence suggests that genetic factors partially influence overall risk of illness but also influence the sensitivity of individuals to the depressogenic effects of environmental adversity.
Fava, Maurizio, Kendler, Kenneth S
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Efficacy of Ketamine as an Adjuvant to Antidepressants in the Treatment of Depression [PDF]
Journal of Clinical and Diagnostic Research, 2021 Introduction: Depression is the second leading cause of morbidity worldwide. Currently, available antidepressants mostly target the monoamine system. The onset of action and response rates for these antidepressants are varied.
Hrishikesh Solunke +4 more
doaj +1 more source
Treating depressive disorders with the unified protocol: A preliminary randomized evaluation. [PDF]
, 2020 OBJECTIVES: This study aims to examine the efficacy of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP) for individuals diagnosed with a depressive disorder. METHOD: Participants included 44 adults who met criteria for major
Ametaj, Amantia A. +9 more
core +2 more sources