Results 31 to 40 of about 522,565 (283)

Neurobiology of Major Depressive Disorder

Neural Plasticity, 2013
We survey studies which relate abnormal neurogenesis to major depressive disorder. Clinically, descriptive gene and protein expression analysis and genetic and functional studies revised here show that individual alterations of a complex signaling ...
Rosa Villanueva
doaj   +1 more source

Tobacco smoking as a risk factor for major depressive disorder : a population-based study

, 2008
Background : Smoking is disproportionately prevalent among people with psychiatric illness. Aims : To investigate smoking as a risk factor for major depressive disorder. Method : A population-based sample of women was studied using case–control and
Berk, Michael, Henry, Margaret J., Jacka, Felice N., Kotowicz, Mark A., Ng, Felicity, Nicholson, Geoffrey C., Pasco, Julie A., Williams, Lana J.   +7 more
core   +1 more source

Prevalence and correlates of depressive disorders in people with Type 2 diabetes: results from the International Prevalence and Treatment of Diabetes and Depression (INTERPRET‐DD) study, a collaborative study carried out in 14 countries [PDF]

, 2018
Aims To assess the prevalence and management of depressive disorders in people with Type 2 diabetes in different countries. Methods People with diabetes aged 18–65 years and treated in outpatient settings were recruited in 14 countries and underwent
Ahmed, H. U., Alvarez, A., Bahendeka, S., Basangwa, D., Boborov, A. E., Boden, S., Bulgari, V., Burti, L., Chaturvedi, S. K., Cimino, L. C., de Girolamo, G., Gaebel, W., Gondek, T. M., Guinzbourg de Braude, M., Guntupalli, A., Heinze, M. G., Hong, X., Ji, L., Kamala, T., Khan, A., Kiejna, A., Kokoszka, A., Lalic, N. M., Lecic Tosevski, D., Li, M., Lloyd, C. E., Mankovsky, B., Musau, A., Mussig, K., Ndetei, D., Nouwen, A., Rabbani, G., Sartorius, N., Shevchuk, M., Srikanta, S. S., Starostina, E. G., Taj, R., Vukovic, O., Wolwer, W., Xin, Y.   +39 more
core   +2 more sources

Immature defense mechanisms predict poor response to psychotherapy in major depressive patients with comorbid cluster B personality disorder

Brazilian Journal of Psychiatry, 2022
Objective: To evaluate the impact of defense mechanisms at baseline on depressive symptoms after brief psychotherapies and after 6-months of follow-up among depressed patients with and without cluster B personality disorders (PDs).
Carolina Rheingantz Scaini, Igor Soares Vieira, Rosiene Machado, Taiane de Azevedo Cardoso, Thaise Mondin, Luciano Souza, Mariane Lopez Molina, Karen Jansen, Ricardo Azevedo da Silva   +8 more
doaj   +1 more source

Case management for the treatment of patients with major depression in general practices – rationale, design and conduct of a cluster randomized controlled trial – PRoMPT (primary care monitoring for depressive patient's trial) [ISRCTN66386086] – Study protocol [PDF]

, 2005
Background: Depression is a disorder with high prevalence in primary health care and a significant burden of illness. The delivery of health care for depression, as well as other chronic illnesses, has been criticized for several reasons and new ...
Jochen Gensichen, Marion Torge, Monika Peitz, Heike Wendt-Hermainski, Martin Beyer, Thomas Rosemann, Christian Krauth, Heiner Raspe, Josef B Aldenhoff, Ferdinand M Gerlach, J Ormel, J Ormel, D Kamerow, T Ustun, A Shah, G Simon, T Bodenheimer, B Ahrens, J Fritze, A Coulter, T Os van, M Von Korff, S Norris, S Gilbody, J Gensichen, MK Campbell, MK Campbell, B Löwe, RJ Hayes, S Banerjee, MK Campbell, A Beck, D Moriskey, M Bullinger, EuroQOL-Group   +34 more
core   +1 more source

Retinoid homeostasis in major depressive disorder

Translational Psychiatry, 2023
The small, hormone-like molecule retinoic acid (RA) is a vital regulator in several neurobiological processes that are affected in depression. Next to its involvement in dopaminergic signal transduction, neuroinflammation, and neuroendocrine regulation ...
Lisa Rebecca Otto, Vera Clemens, Berk Üsekes, Nicoleta Carmen Cosma, Francesca Regen, Julian Hellmann-Regen   +5 more
doaj   +1 more source

Non-REM sleep in major depressive disorder

NeuroImage: Clinical, 2022
Disturbed sleep is a key symptom in major depressive disorder (MDD). REM sleep alterations are well described in the current literature, but little is known about non-REM sleep alterations.
Leonore Bovy, Frederik D. Weber, Indira Tendolkar, Guillén Fernández, Michael Czisch, Axel Steiger, Marcel Zeising, Martin Dresler   +7 more
doaj   +1 more source

Failure of hippocampal deactivation during loss events in treatment-resistant depression [PDF]

, 2015
Major depressive disorder is characterized by anhedonia, cognitive biases, ruminations, hopelessness and increased anxiety. Blunted responses to rewards have been reported in a number of recent neuroimaging and behavioural studies of major depressive ...
Blair A. Johnston, Cavanagh, David Christmas, J. Douglas Steele, Keith Matthews, Ma, Serenella Tolomeo, Victoria Gradin, Zhang   +8 more
core   +2 more sources

The association between mood and anxiety disorders, and coronary heart disease in Brazil: a cross-sectional analysis on the Brazilian longitudinal study of adult health (ELSA-Brasil) [PDF]

, 2015
Background: Associations between major depressive disorder and coronary heart disease (CHD) have been established, and these associations increase risk of future morbidity and mortality. Prior research has been carried out in high-income countries.
Andrade, Aquino, Brunoni, Buckley, Busnello, Craig, Dantzer, de Jesus Mari, Doering, Field, Filho, Hamer, Kemp, Kemp, Kemp, Kemp, Lewis, Lichtman, Mari, Mari, Nemeroff, Nunes, Ramasubbu, Ramasubbu, Ribeiro, Russ, Schmidt, Simon, Smoller, Stapelberg, Tully, Tully, Vogelzangs, Whang, Wilkinson   +34 more
core   +2 more sources

Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim, Han Gil Seo, Roh‐Eul Yoo, Byung‐Mo Oh   +3 more
wiley   +1 more source