Results 11 to 20 of about 522,565 (283)

Sparse whole-genome sequencing identifies two loci for major depressive disorder. [PDF]

open access: yesNature, 2015
Major depressive disorder (MDD), one of the most frequently encountered forms of mental illness and a leading cause of disability worldwide, poses a major challenge to genetic analysis.
CONVERGE consortium
core   +3 more sources

Ketamine: A New Antidepressant? [PDF]

open access: yesPsikiyatride Güncel Yaklaşımlar, 2015
Standart antidepressants are needed for the many individuals with major depressive disorder. However they do not respond adequately to treatment and because of a delay of weeks before the emergence of therapeutic effects.
Feride Karacaer
doaj   +1 more source

Adult Separation Anxiety Disorder in the Geriatric Population with Major Depressive Disorder

open access: yesNeuropsychiatric Investigation, 2022
Objective: Separation anxiety disorder is a disorder with childhood-onset, which manifests itself also in adulthood and is often comorbid with other psychiatric disorders.
Feride Yıldırım, Aslı Beşirli
doaj   +1 more source

Real-world assessment of treatment inertia in the management of patients treated for major depressive disorder in the USA

open access: yesJournal of Comparative Effectiveness Research, 2023
Aim: Major depressive disorder (MDD) is a debilitating illness in which depressive symptoms may persist after treatment. Treatment inertia is the continued use of the same pharmacotherapy regimen when treatment goals are not met.
John J Sheehan   +6 more
doaj   +1 more source

Brain aging in major depressive disorder

open access: yesEuropean Psychiatry, 2021
Depression and anxiety are common and often comorbid mental health disorders that represent risk factors for aging-related conditions. Brain aging has shown to be more advanced in patients with Major Depressive Disorder (MDD).
L. Han   +7 more
doaj   +1 more source

Comorbid depressive disorders in ADHD. the role of ADHD severity, subtypes and familial psychiatric disorders [PDF]

open access: yes, 2014
ObjectiveaaTo evaluate the presence of Major Depressive Disorder (MDD) and Dysthymic Disorder (DD) in a sample of Italian children with Attention Deficit Hyperactivity Disorder (ADHD) and to explore specific features of comorbid depressive disorders in ...
Andriola E   +6 more
core   +1 more source

What patients with bipolar disorder and major depressive disorder perceive as adverse life events precipitating a current major depressive episode

open access: yesSouth African Journal of Psychiatry, 2015
Background. Adverse life events (ALEs) as precipitants of a major depressive episode (MDE) have been the subject of many studies. These studies indicate an increase in ALEs in the 6 months preceding an MDE. Objectives.
Robyn Anne van Schoor, Pierre M Joubert
doaj   +1 more source

Major depressive disorder in detention officers

open access: yesRevista de Saúde Pública, 2021
OBJECTIVE To identify factors associated with major depressive disorder (MDD) in detention officers. METHODS This cross-sectional study included all detention officers from the largest prison complex in the state of Bahia, Brazil.
Sheila Nascimento Santos   +3 more
doaj   +2 more sources

Microstructural Correlates of Resilience against Major Depressive Disorder: Epigenetic Mechanisms? [PDF]

open access: yes, 2010
Mental disorders are a major cause of long-term disability and are a direct cause of mortality, with approximately 800.000 individuals dying from suicide every year worldwide - a high proportion of them related to major depressive disorder (MDD)^1 ...
Andrew Fagan   +8 more
core   +3 more sources

Lipidomics in Major Depressive Disorder

open access: yesFrontiers in Psychiatry, 2018
Omic sciences coupled with novel computational approaches such as machine intelligence offer completely new approaches to major depressive disorder (MDD) research.
Andreas Walther   +7 more
doaj   +1 more source

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