Results 11 to 20 of about 514,237 (285)

Real-world assessment of treatment inertia in the management of patients treated for major depressive disorder in the USA

Journal of Comparative Effectiveness Research, 2023
Aim: Major depressive disorder (MDD) is a debilitating illness in which depressive symptoms may persist after treatment. Treatment inertia is the continued use of the same pharmacotherapy regimen when treatment goals are not met.
John J Sheehan, Chris LaVallee, Keshia Maughn, Santosh Balakrishnan, Jacqueline A Pesa, Kruti Joshi, Craig Nelson   +6 more
doaj   +1 more source

Ketamine: A New Antidepressant? [PDF]

Psikiyatride Güncel Yaklaşımlar, 2015
Standart antidepressants are needed for the many individuals with major depressive disorder. However they do not respond adequately to treatment and because of a delay of weeks before the emergence of therapeutic effects.
Feride Karacaer
doaj   +1 more source

Brain aging in major depressive disorder

European Psychiatry, 2021
Depression and anxiety are common and often comorbid mental health disorders that represent risk factors for aging-related conditions. Brain aging has shown to be more advanced in patients with Major Depressive Disorder (MDD).
L. Han, H. Schnack, R. Brouwer, D. Veltman, N. Van Der Wee, M.-J. Van Tol, M. Aghajani, B. Penninx   +7 more
doaj   +1 more source

Major depressive disorder in detention officers

Revista de Saúde Pública, 2021
OBJECTIVE To identify factors associated with major depressive disorder (MDD) in detention officers. METHODS This cross-sectional study included all detention officers from the largest prison complex in the state of Bahia, Brazil.
Sheila Nascimento Santos, Kionna Oliveira Bernardes Santos, Fernando Martins Carvalho, Rita de Cássia Pereira Fernandes   +3 more
doaj   +2 more sources

Failure of hippocampal deactivation during loss events in treatment-resistant depression [PDF]

, 2015
Major depressive disorder is characterized by anhedonia, cognitive biases, ruminations, hopelessness and increased anxiety. Blunted responses to rewards have been reported in a number of recent neuroimaging and behavioural studies of major depressive ...
Blair A. Johnston, Cavanagh, David Christmas, J. Douglas Steele, Keith Matthews, Ma, Serenella Tolomeo, Victoria Gradin, Zhang   +8 more
core   +2 more sources

Prevalence and correlates of depressive disorders in people with Type 2 diabetes: results from the International Prevalence and Treatment of Diabetes and Depression (INTERPRET‐DD) study, a collaborative study carried out in 14 countries [PDF]

, 2018
Aims To assess the prevalence and management of depressive disorders in people with Type 2 diabetes in different countries. Methods People with diabetes aged 18–65 years and treated in outpatient settings were recruited in 14 countries and underwent
Ahmed, H. U., Alvarez, A., Bahendeka, S., Basangwa, D., Boborov, A. E., Boden, S., Bulgari, V., Burti, L., Chaturvedi, S. K., Cimino, L. C., de Girolamo, G., Gaebel, W., Gondek, T. M., Guinzbourg de Braude, M., Guntupalli, A., Heinze, M. G., Hong, X., Ji, L., Kamala, T., Khan, A., Kiejna, A., Kokoszka, A., Lalic, N. M., Lecic Tosevski, D., Li, M., Lloyd, C. E., Mankovsky, B., Musau, A., Mussig, K., Ndetei, D., Nouwen, A., Rabbani, G., Sartorius, N., Shevchuk, M., Srikanta, S. S., Starostina, E. G., Taj, R., Vukovic, O., Wolwer, W., Xin, Y.   +39 more
core   +2 more sources

What patients with bipolar disorder and major depressive disorder perceive as adverse life events precipitating a current major depressive episode

South African Journal of Psychiatry, 2015
Background. Adverse life events (ALEs) as precipitants of a major depressive episode (MDE) have been the subject of many studies. These studies indicate an increase in ALEs in the 6 months preceding an MDE. Objectives.
Robyn Anne van Schoor, Pierre M Joubert
doaj   +1 more source

Comorbid depressive disorders in ADHD. the role of ADHD severity, subtypes and familial psychiatric disorders [PDF]

, 2014
ObjectiveaaTo evaluate the presence of Major Depressive Disorder (MDD) and Dysthymic Disorder (DD) in a sample of Italian children with Attention Deficit Hyperactivity Disorder (ADHD) and to explore specific features of comorbid depressive disorders in ...
Andriola E, Di Roma F, DI TRANI, MICHELA, Donfrancesco R., Leone D, Miano S, PARISI, Pasquale   +6 more
core   +1 more source

Sensor-AssistedWeighted Average Ensemble Model for Detecting Major Depressive Disorder [PDF]

, 2019
The present methods of diagnosing depression are entirely dependent on self-report ratings or clinical interviews. Those traditional methods are subjective, where the individual may or may not be answering genuinely to questions.
Chang, Chuan-Yu, Gao, Liang, Garg, Akhil, Gutiérrez Reina, Daniel, Mahendran, Nivedhitha, Srinivasan, Kathiravan, Vincent, Durai Raj   +6 more
core   +1 more source

A gene co-expression network-based analysis of multiple brain tissues reveals novel genes and molecular pathways underlying major depression.

PLoS Genetics, 2019
Major depression is a common and severe psychiatric disorder with a highly polygenic genetic architecture. Genome-wide association studies have successfully identified multiple independent genetic loci that harbour variants associated with major ...
Zachary F Gerring, Eric R Gamazon, Eske M Derks, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium   +3 more
doaj   +1 more source