Results 71 to 80 of about 3,916,339 (374)

Should antidepressants be used for major depressive disorder?

BMJ evidence-based medicine, 2019
Background Major depressive disorder is estimated by the WHO to affect more than 300 million people globally, making depression the leading cause of disability worldwide. Antidepressants are commonly used to treat depression. Objective The study aimed to
J. Jakobsen, C. Gluud, I. Kirsch
semanticscholar   +1 more source

How major depressive disorder affects the ability to decode multimodal dynamic emotional stimuli [PDF]

, 2016
Most studies investigating the processing of emotions in depressed patients reported impairments in the decoding of negative emotions. However, these studies adopted static stimuli (mostly stereotypical facial expressions corresponding to basic emotions)
Esposito, Anna, Likforman-Sulem, Laurence, Scibelli, Filomena, Troncone, Alda, Vinciarelli, Alessandro   +4 more
core   +2 more sources

The Impact of Tilburg Frailty on Poststroke Fatigue in First‐Ever Stroke Patients: A Cross‐Sectional Study With Unified Measurement Tools and Improved Statistics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen, Xiao‐Xue Wang, Shao‐Rui Bao, Sui‐Li Lin, Mei‐Chun Shu, Xi‐Xi Ye, Wen‐Jie Cong   +6 more
wiley   +1 more source

Glymphatic dysfunction associated with cortisol dysregulation in major depressive disorder

Translational Psychiatry
Cortisol dysregulation plays a critical role in the pathophysiology of depression, but its exact impact on the brain remains unclear. In this cross-sectional study, 210 participants, including 164 depressed patients and 46 healthy controls (HCs), were ...
Shengli Chen, Ziyun Xu, Zheng Guo, Shiwei Lin, Hongyuan Zhang, Qunjun Liang, Qianyun Chen, Yingli Zhang, Bo Peng, Yanzhen Zhao, Gangqiang Hou, Yingwei Qiu   +11 more
doaj   +1 more source

Perbedaan Proporsi Gangguan Depresi dan Gangguan Cemas Antara Mahasiswa Preklinik dan Klinik

Jurnal Pendidikan Kedokteran Indonesia, 2017
Background: Medical education is full of burden and pressure, so that medical students are prone to get depressive disorder and anxiety disorder. These have been proven by several researches conducted in the faculties of medicine from abroad as well as ...
Yoan Chou, Dharmady Agus, Dwi Jani Juliawati   +2 more
doaj   +1 more source

Examining cognition across the bipolar / schizophrenia diagnostic spectrum [PDF]

, 2018
BACKGROUND: Cognitive impairments are well-established features of schizophrenia, but there is ongoing debate about the nature and degree of cognitive impairment in patients with schizoaffective disorder and bipolar disorder.
Hamshere, Marian L., Hubbard, Leon, Jones, Ian, Legge, Sophie, Lynham, Amy, Owen, Michael, Tansey, Katherine, Walters, James   +7 more
core   +1 more source

Relapsing–Remitting Multiple Sclerosis Is Associated With a Dysbiotic Oral Microbiome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurological impairment. While the gut microbiota's role in MS is extensively studied, the association between the oral microbiota and MS remains underexplored, particularly in North American cohorts.
Sukirth M. Ganesan, Meeta Yadav, Sudeep Ghimire, Peter C. Lehman, Apurva J. Patel, Sydney Woods, Heena Olalde, Jemmie Hoang, Mishelle Paullus, Catherine Cherwin, Christine Gill, Tracey Cho, Ashutosh K. Mangalam   +12 more
wiley   +1 more source

Major Depressive Disorder

South African Journal of Psychiatry, 2013
The treatment guideline draws on several international guidelines: (i)Practice Guidelines of the American Psychiatric Association (APA)for the Treatment of Patients with Major Depressive Disorder, SecondEdition;[1](ii) Clinical Guidelines for the ...
G Grobler
doaj   +1 more source

Transdiagnostic treatment of bipolar disorder and comorbid anxiety using the Unified Protocol for Emotional Disorders: A pilot feasibility and acceptability trial [PDF]

, 2017
BACKGROUND Comorbid anxiety in bipolar disorder (BD) is associated with greater illness severity, reduced treatment response, and greater impairment. Treating anxiety in the context of BD is crucial for improving illness course and outcomes. The current
Baek, Ji Hyun, Barlow, David H., Bernstein, Emily E., Deckersbach, Thilo, Ellard, Kristen K., Hearing, Casey, Nierenberg, Andrew A., Sylvia, Louisa G.   +7 more
core   +1 more source

Nationwide Survey of Atopic Myelitis and Plexin D1‐Immunoglobulin G‐Related Pain

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To elucidate the features of plexin D1‐immunoglobulin (Ig)G‐associated neuropathic pain and its relationship to atopic myelitis (AM) in a nationwide Japanese survey. Methods A preliminary survey questionnaire was sent to 1574 selected departments (neurology and pediatrics/pediatric neurology) to explore the numbers of AM and plexin ...
Jun‐ichi Kira, Xu Zhang, Takayuki Fujii, Mikio Mitsuishi, Miho Ushijima, Sato Yoshidomi, Ayako Sakoda, Tomohiro Imamura, Satoshi Kuwabara, Noriko Isobe, Yuri Nakamura   +10 more
wiley   +1 more source