Results 81 to 90 of about 3,916,339 (374)

Epigenetic Aging in Major Depressive Disorder.

American Journal of Psychiatry, 2018
OBJECTIVE Major depressive disorder is associated with an increased risk of mortality and aging-related diseases. The authors examined whether major depression is associated with higher epigenetic aging in blood as measured by DNA methylation (DNAm ...
Laura K. M. Han, M. Aghajani, S. Clark, R. Chan, M. Hattab, A. Shabalin, Min Zhao, G. Kumar, Lin Y. Xie, R. Jansen, Y. Milaneschi, B. Dean, K. Åberg, E. J. van den Oord, B. Penninx   +14 more
semanticscholar   +1 more source

Psychopathology in Williams syndrome: the effect of individual differences across the lifespan [PDF]

, 2009
The present research aimed to comprehensively explore psychopathology in Williams syndrome (WS) across the lifespan and evaluate the relationship between psychopathology and age category (child or adult), gender and cognitive ability.
American Psychiatric Association, American Psychiatric Association, Helen F. Dodd, Jefferys D., Karmiloff-Smith A., Kaufman J., Melanie A. Porter, Mervis C. B., Pober B. R., Silverman W. K., Soni S., Switaj D. M., Woodcock R. W.   +12 more
core   +1 more source

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source

Altered levels of malondialdehyde and vitamin E in major depressive disorder and generalized anxiety disorder [PDF]

Düşünen Adam Psikiyatri ve Nörolojik Bilimler Dergisi, 2012
Introduction: Reactive oxygen species (ROS) may play a role in some neuropsychiatric disorders. There is some evidence that the activation of immune-inflammatory processes, an increase in monoamines catabolism and abnormalities in lipid compounds may ...
kemal yazici, aylin yazici, şenel tot acar, nilgun bal, lulufer tamer   +4 more
doaj  

Cognitive impairment in major depressive disorder

CNS Spectrums, 2018
Cognitive dysfunction is a symptomatic domain identified across many mental disorders. Cognitive deficits in individuals with major depressive disorder (MDD) contribute significantly to occupational and functional disability.
Z. Pan, Caroline Park, E. Brietzke, Hannah Zuckerman, Carola Rong, R. Mansur, Dominika Fus, Mehala Subramaniapillai, Yena Lee, R. McIntyre   +9 more
semanticscholar   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Recognition and Treatment of Cognitive Dysfunction in Major Depressive Disorder

Frontiers in Psychiatry, 2018
Major Depressive Disorder (MDD) is a prevalent, chronic, disabling, and multidimensional mental disorder. Cognitive dysfunction represents a core diagnostic and symptomatic criterion of MDD, and is a principal determinant of functional non-recovery ...
Hannah Zuckerman, Z. Pan, Caroline Park, E. Brietzke, Natalie Musial, Aisha S. Shariq, M. Iacobucci, Samantha J. Yim, L. Lui, Carola Rong, R. McIntyre   +10 more
semanticscholar   +1 more source

DEPRESSIVE DISORDERS AND COMORBIDITY: SOMATIC ILLNESS VS. SIDE EFFECT [PDF]

, 2009
Background: The rate of comorbid depression and medical illness varies from 10 to 40%. Patients with depressive disorder compared to general population more often have cardiovascular and cerebrovascular disorders, diabetes, irritable bowel syndrome, and ...
Miro Jakovljević, Oliver Kozumplik, Radmila Topić, Suzana Uzun   +3 more
core   +1 more source

Shame, depressive symptoms and eating, weight and shape concerns in a non-clinical sample [PDF]

, 2003
Shame has been shown to be related both to symptoms of depression and eating pathology. However, the independence of this relationship has not yet been established.
Gee, Alice, Troop, Nicholas
core   +1 more source

Childhood depressive disorders. [PDF]

Danish medical journal, 2016
Major depressive disorder (MDD) is a frequent and painful mental disorder considered among the five leading causes of disability in Western countries by the World Health Organization. MDD occurs at all ages, but childhood onset MDD has a more severe course with longer depressive episodes, more suicidality, and more frequent hospitalization, than later ...
openaire   +3 more sources