Results 81 to 90 of about 3,696,874 (383)

Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group

Molecular Psychiatry, 2015
The pattern of structural brain alterations associated with major depressive disorder (MDD) remains unresolved. This is in part due to small sample sizes of neuroimaging studies resulting in limited statistical power, disease heterogeneity and the ...
L. Schmaal, D. Veltman, T. V. Erp, P. Sämann, T. Frodl, T. Frodl, N. Jahanshad, E. Loehrer, H. Tiemeier, A. Hofman, W. Niessen, W. Niessen, M. Vernooij, M. Ikram, K. Wittfeld, H. Grabe, A. Block, K. Hegenscheid, H. Völzke, D. Hoehn, M. Czisch, J. Lagopoulos, S. Hatton, I. Hickie, R. Goya-Maldonado, B. Krämer, O. Gruber, B. Couvy-Duchesne, B. Couvy-Duchesne, M. Rentería, Lachlan T. Strike, Lachlan T. Strike, Natalie T. Mills, Natalie T. Mills, G. Zubicaray, K. Mcmahon, S. Medland, N. Martin, N. Gillespie, M. Wright, G. Hall, G. MacQueen, Eva-Maria Frey, A. Carballedo, L. V. Velzen, M. V. Tol, N. Wee, I. Veer, Henrik Walter, K. Schnell, E. Schramm, C. Normann, D. Schoepf, C. Konrad, B. Zurowski, T. Nickson, A. McIntosh, M. Papmeyer, H. Whalley, J. Sussmann, B. Godlewska, P. Cowen, Felix H Fischer, Matthias Rose, M. Rose, B. Penninx, P. Thompson, D. Hibar   +67 more
semanticscholar   +1 more source

NOTCH2NLC Repeat Expansions in Parkinsonian Disorders: Clinical and Neuroimaging Characteristics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuronal intranuclear inclusion disease (NIID) is a neurodegenerative disorder caused by NOTCH2NLC GGC repeat expansions, with heterogeneous clinical manifestations, including parkinsonism. Recent studies have identified NOTCH2NLC repeat expansions in patients with Parkinson's disease (PD) and atypical parkinsonism (aPM), suggesting ...
Han‐Lin Chiang, Kang‐Yang Jih, Cheng‐Tsung Hsiao, Fu‐Pang Chang, Justus Chunyu Chen, Yi‐Chu Liao, Yih‐Ru Wu, Yi‐Chung Lee   +7 more
wiley   +1 more source

Prevalence of depressive disorder among elderly people in China： a Meta-analysis

Sichuan jingshen weisheng
BackgroundDepressive disorder is one of the most common mental disorders in the elderly and the existing meta-analyses on the prevalence of depressive disorder among the elderly have mainly summarized the findings from patient self-rating scales or ...
Wu Ping, Huang Guangbiao, Tan Zhonglin, Wu Yue, Liang Sugai   +4 more
doaj   +1 more source

How major depressive disorder affects the ability to decode multimodal dynamic emotional stimuli [PDF]

, 2016
Most studies investigating the processing of emotions in depressed patients reported impairments in the decoding of negative emotions. However, these studies adopted static stimuli (mostly stereotypical facial expressions corresponding to basic emotions)
Esposito, Anna, Likforman-Sulem, Laurence, Scibelli, Filomena, Troncone, Alda, Vinciarelli, Alessandro   +4 more
core   +2 more sources

Sparse whole genome sequencing identifies two loci for major depressive disorder

Nature, 2015
Major depressive disorder (MDD), one of the most frequently encountered forms of mental illness and a leading cause of disability worldwide, poses a major challenge to genetic analysis.
N. Cai, T. Bigdeli, Warren W. Kretzschmar, Yihan Li, Jieqin Liang, Li Song, Jingchu Hu, Qibin Li, Wei Jin, Zhenfei Hu, Guangbiao Wang, Linmao Wang, Puyi Qian, Yuan Liu, T. Jiang, Yao Lu, Xiuqing Zhang, Ye Yin, Yingrui Li, Xun Xu, Jingfang Gao, M. Reimers, T. Webb, B. Riley, S. Bacanu, Roseann E. Peterson, Yiping Chen, H. Zhong, Zhengrong Liu, Gang Wang, Jing Sun, H. Sang, G. Jiang, Xiaoyan Zhou, Yi Li, Wei Zhang, Xueyi Wang, X. Fang, R. Pan, G. Miao, Qiwen Zhang, Jian Hu, F. Yu, B. Du, W. Sang, K. Li, Guibing Chen, M. Cai, Lijun Yang, Donglin Yang, B. Ha, X. Hong, H. Deng, Gongying Li, Kan Li, Yan Song, Shugui Gao, Jinbei Zhang, Z. Gan, H. Meng, J. Pan, C. Gao, Kerang Zhang, N. Sun, Youhui Li, Q. Niu, Y Zhang, Tieqiao Liu, Chunmei Hu, Zhen Zhang, L. Lv, Jicheng Dong, Xiao-ping Wang, M. Tao, Xumei Wang, Jing Xia, H. Rong, Qiang He, Tie-bang Liu, Guoping Huang, Q. Mei, Zhenming Shen, Y. Liu, Jianhua Shen, T. Tian, Xiaojuan Liu, Wenyuan Wu, D. Gu, G. Fu, Jian-guo Shi, Yunchun Chen, Xiangchao Gan, Lan-fen Liu, Lina Wang, Fuzhong Yang, E. Cong, J. Marchini, Huanming Yang, Jian Wang, S. Shi, R. Mott, Qi Xu, Jun Wang, K. Kendler, J. Flint   +104 more
semanticscholar   +1 more source

Central Dysmyelination in SSADH‐Deficient Humans and Mice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer, Henry H. C. Lee, Edward Yang, Cesar Alves, Mariarita Bertoldi, Caitlyn Fung, Spencer V. Steele, Eren Kule, Zijie Jin, Alexander Rotenberg, Jean‐Baptiste Roullet, Phillip L. Pearl   +11 more
wiley   +1 more source

DEPRESSIVE DISORDERS AND COMORBIDITY: SOMATIC ILLNESS VS. SIDE EFFECT [PDF]

, 2009
Background: The rate of comorbid depression and medical illness varies from 10 to 40%. Patients with depressive disorder compared to general population more often have cardiovascular and cerebrovascular disorders, diabetes, irritable bowel syndrome, and ...
Miro Jakovljević, Oliver Kozumplik, Radmila Topić, Suzana Uzun   +3 more
core   +1 more source

Psychopathology in Williams syndrome: the effect of individual differences across the lifespan [PDF]

, 2009
The present research aimed to comprehensively explore psychopathology in Williams syndrome (WS) across the lifespan and evaluate the relationship between psychopathology and age category (child or adult), gender and cognitive ability.
American Psychiatric Association, American Psychiatric Association, Helen F. Dodd, Jefferys D., Karmiloff-Smith A., Kaufman J., Melanie A. Porter, Mervis C. B., Pober B. R., Silverman W. K., Soni S., Switaj D. M., Woodcock R. W.   +12 more
core   +1 more source

Cognitive impairment in major depressive disorder

CNS Spectrums, 2018
Cognitive dysfunction is a symptomatic domain identified across many mental disorders. Cognitive deficits in individuals with major depressive disorder (MDD) contribute significantly to occupational and functional disability.
Z. Pan, Caroline Park, E. Brietzke, Hannah Zuckerman, Carola Rong, R. Mansur, Dominika Fus, Mehala Subramaniapillai, Yena Lee, R. McIntyre   +9 more
semanticscholar   +1 more source

Medication Use in Multiple Sclerosis: A Population‐Based Comparison With the General Danish Population

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the overall use of prescription medications among individuals with multiple sclerosis compared to the general population, with a focus on treatments beyond disease‐modifying therapies. Methods We conducted a nationwide, registry‐based study in Denmark.
Josefine Windfeld‐Mathiasen, Henrik Horwitz, Ida M. Heerfordt, Elisabeth Framke, Melinda Magyari   +4 more
wiley   +1 more source