Results 61 to 70 of about 6,958,036 (288)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Depth and Stanley Depth of Multigraded Modules [PDF]
Communications in Algebra, 2010 We study the behavior of depth and Stanley depth along short exact sequences of multigraded modules and under reduction modulo an element.
openaire +2 more sources
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Revisiting the role of breadth and depth of vocabulary knowledge in reading comprehension
Cogent Education, 2023 The purpose of this study was to investigate the role of breadth and depth of vocabulary knowledge in reading comprehension at Debre Markos University. A quantitative approach was taken to gather and analyze the data.
Animut Tadele Dagnaw
doaj +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
npj Cardiovascular HealthLipoproteins, synthesized in the liver and secreted into the bloodstream, play a central role in lipid transport. Although their quality affects cardiovascular outcomes, conventional markers do not fully explain the disease risk.
Hiroaki Takeda +8 more
doaj +1 more source
Distribution of Abundant and Active Planktonic Ciliates in Coastal and Slope Waters Off New England
Frontiers in Microbiology, 2017 Despite their important role of linking microbial and classic marine food webs, data on biogeographical patterns of microbial eukaryotic grazers are limited, and even fewer studies have used molecular tools to assess active (i.e., those expressing genes)
Sarah J. Tucker +4 more
doaj +1 more source
, 2018 Little known relations of the renown concept of the halfspace depth for multivariate data with notions from convex and affine geometry are discussed. Halfspace depth may be regarded as a measure of symmetry for random vectors.
Nagy, Stanislav +2 more
core +1 more source
, 2013 In 1975 John Tukey proposed a multivariate median which is the 'deepest' point in a given data cloud in R^d. Later, in measuring the depth of an arbitrary point z with respect to the data, David Donoho and Miriam Gasko considered hyperplanes through z and determined its 'depth' by the smallest portion of data that are separated by such a hyperplane ...
openaire +2 more sources
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source