Results 31 to 40 of about 474,599 (267)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
The Development of a Sorting System Based on Point Cloud Weight Estimation for Fattening Pigs
AgricultureAs large-scale and intensive fattening pig farming has become mainstream, the increase in farm size has led to more severe issues related to the hierarchy within pig groups.
Luo Liu +5 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
智慧农业ObjectiveThe detection of lameness in dairy cows is an important issue that needs to be solved urgently in the process of large-scale dairy farming. Timely detection and effective intervention can reduce the culling rate of young dairy cows, which has ...
DAI Xin +6 more
doaj +1 more source
Sensors, 2019 Segmentation of human bodies in images is useful for a variety of applications, including background substitution, human activity recognition, security, and video surveillance applications. However, human body segmentation has been a challenging problem,
Jonha Lee +3 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Collaborative Differential Evolution Filtering for Tracking Hand-Object Interactions
IEEE Access, 2020 Human hands engage in interactive activities in many practical working scenarios, among which the interactions between human hands and objects are the most common.
Dongnian Li +3 more
doaj +1 more source
Model reconstruction method of non-structural surface of hull grillage based on RGB-D depth image
Zhongguo Jianchuan Yanjiu, 2023 ObjectivesIn order to reconstruct the 3D shape of the non-structural surface of the hull plate frame accurately and quickly, and lay a foundation for the study on the high-precision and efficient measurement of the hull structure deformation, a model ...
Shuo WANG, Zhen CHEN, Chongben NI
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Hole-Filling of RealSense Depth Images Using a Color Edge Map
IEEE Access, 2020 The RealSense camera frequently includes hole regions-unfilled regions where depth information are missing in the depth image. The holes cause serious problems in applications that use depth sensors and often straddle the background and object ...
Ji-Min Cho +2 more
doaj +1 more source