Results 71 to 80 of about 120,019 (255)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

A Short-Pulse Indirect ToF Imager Using Six-Tap Pixel with a Backside-Illuminated Structure for High-Speed Demodulation

Sensors
This paper evaluates the effectiveness of a backside illumination (BSI) structure in a short-pulse indirect time-of-flight (SP-iToF) sensor employing 6-tap pixels.
Tomohiro Okuyama, Haruya Sugimura, Gabriel Alcade, Seiya Ageishi, Hyeun Woo Kwen, De Xing Lioe, Kamel Mars, Keita Yasutomi, Keiichiro Kagawa, Shoji Kawahito   +9 more
doaj   +1 more source

Estimating Depth from RGB and Sparse Sensing [PDF]

, 2018
We present a deep model that can accurately produce dense depth maps given an RGB image with known depth at a very sparse set of pixels. The model works simultaneously for both indoor/outdoor scenes and produces state-of-the-art dense depth maps at nearly real-time speeds on both the NYUv2 and KITTI datasets.
Zhao Chen 0006, Vijay Badrinarayanan, Gilad Drozdov, Andrew Rabinovich   +3 more
openaire   +3 more sources

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Multi-Path Interference Challenges and Suggested Solution for Correlation-Assisted Direct Time-of-Flight

Sensors
The correlation-assisted direct time-of-flight (CA-dToF) pixel offers a promising approach for low-power consumption, ambient light robustness, and high-resolution depth sensing.
Ayman Morsy, David Blinder, Maarten Kuijk   +2 more
doaj   +1 more source

Spatio-temporal Phase Disambiguation in Depth Sensing

2019 IEEE International Conference on Computational Photography (ICCP), 2019
Phase ambiguity is a major problem in the depth measurement in either time-of-flight or phase shifting. Resolving the ambiguity using a low frequency pattern sacrifices the depth precision, and using multiple frequencies requires a number of observations.
Takahiro Kushida 0001, Kenichiro Tanaka, Takahito Aoto 0002, Takuya Funatomi, Yasuhiro Mukaigawa   +4 more
openaire   +2 more sources

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Adaptive Decentralized Control of Mobile Underwater Sensor Networks and Robots for Modeling Underwater Phenomena

Journal of Sensor and Actuator Networks, 2014
Understanding the dynamics of bodies of water and their impact on the global environment requires sensing information over the full volume of water. In this article, we develop a gradient-based decentralized controller that dynamically adjusts the depth ...
Carrick Detweiler, Sreeja Banerjee, Marek Doniec, Mingshun Jiang, Francesco Peri, Robert F. Chen, Daniela Rus   +6 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source