Low-dose decitabine modulates myeloid-derived suppressor cell fitness via LKB1 in immune thrombocytopenia [PDF]
, 2022 Xiaofei Ni +11 more
openalex +1 more source
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Generalized Derivations With Left Annihilator Conditions in Prime and Semiprime Rings
Discussiones Mathematicae - General Algebra and Applications, 2017 Let R be a prime ring with its Utumi ring of quotients U, C = Z(U) be the extended centroid of R, H and G two generalized derivations of R, L a noncentral Lie ideal of R, I a nonzero ideal of R.
Dhara Basudeb
doaj +1 more source
Osteogenic Differentiation of Human Adipose Tissue-Derived Stem Cells Is Modulated by the miR-26a Targeting of the SMAD1 Transcription Factor [PDF]
, 2007 Ettore Luzi +5 more
openalex +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Boletim da Sociedade Paranaense de MatemáticaThis study presents a comprehensive investigation of soft and upper (lower) soft derivatives within the framework of Molodtsov’s soft set theory, extending it through the introduction of novel and complementary notions: left and right soft derivatives.
Enginoğlu, Serdar, Arslan, Burak
openaire +2 more sources
Этимологические заметки о русском семинарском жаргоне: ВЗЪЕФАНТУЛИТЬ, СМОРОЗИТЬ, АКСИОС(Ы) (= Some Etymological Notes on the Russian Seminarian Slang: VZʺEFANTULITʹ, SMOROZITʹ, AKSIOS(Y)) [PDF]
Slovene, 2013 Три отдельные заметки объединены тем, что рассмотренные в них слова происходят из русского семинарского жаргона и являются грецизмами, причём в двух первых случаях неочевидными, каламбурными.
Игорь Георгиевич Добродомов
doaj
Multiple Organ Engraftment by Bone‐Marrow‐Derived Myofibroblasts and Fibroblasts in Bone‐Marrow‐Transplanted Mice [PDF]
, 2003 Natalie Direkze +9 more
openalex +1 more source