Results 91 to 100 of about 6,167,674 (361)
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg+2 more
wiley +1 more source
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
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Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel+2 more
wiley +1 more source
Current progress in the derivation and therapeutic application of neural stem cells
Neural stem cells (NSCs) have a unique role in neural regeneration. Cell therapy based on NSC transplantation is a promising tool for the treatment of nervous system diseases.
Yuewen Tang, Pei Yu, Lin Cheng
semanticscholar +1 more source
DERIVATIONS AND SKEW DERIVATIONS OF THE GRASSMANN ALGEBRAS [PDF]
Surprisingly, skew derivations rather than ordinary derivations are more basic (important) object in study of the Grassmann algebras. Let Λn = K ⌊x1, …, xn⌋ be the Grassmann algebra over a commutative ring K with ½ ∈ K, and δ be a skew K-derivation of Λn.
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Pond, F. J., Beers, F. T.
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To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche+2 more
wiley +1 more source
The scrypt Password-Based Key Derivation Function
This document specifies the password-based key derivation function scrypt. The function derives one or more secret keys from a secret string. It is based on memory-hard functions, which offer added protection against attacks using custom hardware.
Colin Percival, S. Josefsson
semanticscholar +1 more source
On derivations and generalized derivations of bitonic algebras
We introduce the notion of bitonic algebras as a generalization of dual BCCalgebras, and define the notion of (r,l)-derivations, (l,r)-derivations and generalized (r,l) and (l,r)-derivations on the bitonic algebras. Then we study the properties of the derivations and the generalized derivations on the bitonic algebras and the commutative ...
Yon, Y.H., Ayar Ozbal, S.
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Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source