Results 121 to 130 of about 5,342,052 (371)

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha   +6 more
wiley   +1 more source

Left-symmetric algebras of derivations of free algebras [PDF]

open access: yesComm. Algebra 45 (2017), no. 7, 2809--2820, 2014
A structure of a left-symmetric algebra on the set of all derivations of a free algebra is introduced such that its commutator algebra becomes the usual Lie algebra of derivations. Left and right nilpotent elements of left-symmetric algebras of derivations are studied.
arxiv  

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Characterizations of 2-local derivations and local Lie derivations on some algebras [PDF]

open access: yesarXiv, 2016
We prove that every 2-local derivation from the algebra $M_n(\mathcal{A})(n>2)$ into its bimodule $M_n(\mathcal{M})$ is a derivation, where $\mathcal{A}$ is a unital Banach algebra and $\mathcal{M}$ is a unital $\mathcal{A}$-bimodule such that each Jordan derivation from $\mathcal{A}$ into $\mathcal{M}$ is an inner derivation, and that every 2-local ...
arxiv  

On the estimation of the derivatives of a function with the derivatives of an estimate

open access: yesJournal of Multivariate Analysis, 1989
AbstractLet θ̂n(x) be an estimator of a smooth function θ(x). It is proved that θ(x) can be estimated easier than its derivative θ(s)(x), providing for |θ̂n(s) − θ(s)|q an upper bound that depends on |θ̂n − θ|q. The same bound can be used as a tool to derive automatically rates of convergence when we are estimating derivatives of densities or ...
openaire   +3 more sources

Derivation and validation of a prognostic model for pulmonary embolism.

open access: yesAmerican Journal of Respiratory and Critical Care Medicine, 2005
RATIONALE An objective and simple prognostic model for patients with pulmonary embolism could be helpful in guiding initial intensity of treatment. OBJECTIVES To develop a clinical prediction rule that accurately classifies patients with pulmonary ...
D. Aujesky   +7 more
semanticscholar   +1 more source

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