Results 131 to 140 of about 5,312,572 (347)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

DERIVATIONAL MECHANISMS FOR MODELING OCCASIONAL VOCABULARY IN THE RUSSIANLANGUAGE MEDIA SPACE (ON THE EXAMPLE OF THE PREFIX DE-)

open access: yesIzvestiâ Ûžnogo Federalʹnogo Universiteta: Filologičeskie Nauki
This study is devoted to the study of the implementation features of derivational mechanisms for modeling occasional vocabulary in the Russian-language media space.
Anatoliy P. Chudinov   +2 more
doaj   +1 more source

Derivation in English: Names of professions and their translation into Serbian [PDF]

open access: yesZbornik radova (Univerzitet u Kragujevcu. Pedagoški fakultet u Užicu), 2018
Derivation is one among the many processes of word-formation in English. It is a word-formation process by which a new word is produced from an already existing one by adding affixes (prefixes, infixes or suffixes) to a base.
Ljubičić Gordana M.
doaj  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Patient-derived antibodies reveal the subcellular distribution and heterogeneous interactome of LGI1

open access: green, 2022
Jorge Ramírez‐Franco   +17 more
openalex   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery.

open access: yesCirculation, 1999
Thomas H. Lee   +12 more
semanticscholar   +1 more source

Derivation of toxicity equivalency factors for marine biotoxins associated with Bivalve Molluscs [PDF]

open access: green, 2016
Luís M. Botana   +12 more
openalex   +1 more source

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