Results 131 to 140 of about 641,705 (295)

Orchard navigation using derivative free Kalman filtering

open access: yes, 2011
This paper describes the use of derivative free filters for mobile robot localization and navigation in an orchard. The localization algorithm fuses odometry and gyro measurements with line features representing the surrounding fruit trees of the orchard.
Ravn, Ole   +11 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

A partially derivative-free cyclic block coordinate descent method for nonseparable composite optimization

open access: yesMathematical Modelling and Analysis
In this paper, we address a composite optimization problem in which the objective function consists of two terms: the first presents a function with a gradient that satisfies a Lipschitz–Hölder composition, while the second one is a convex function ...
Vitaliano Amaral
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Free vibration analysis of plates and shells by using the Superposition Method

open access: yes, 2010
This thesis is devoted to investigate the capability of the Superposition Method for obtaining the transient response of plates and the natural frequencies of thin doubly curved shallow shells.
Mochida, Yusuke
core  

A derivative-free iterative method for simultaneously computing an arbitrary number of zeros of nonlinear equations

open access: yes, 2012
A new two-point iterative method for solving nonlinear equations is presented. This is a derivative-free method for the simultaneous determination of several or all of the simple zeros.
Nedzhibov, Gyurhan H.
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Tissue-direct PCR, a rapid and extraction-free method for barcoding of ferns

open access: yes, 2012
Tissue-direct PCR, a rapid and extraction-free method for barcoding of ferns
core   +1 more source

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