Results 51 to 60 of about 1,072,002 (279)
Derivative-free discrete gradient methods
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Myhr, Håkon Noren, Eidnes, Sølve
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ABSTRACT Background/Objectives Outcomes for pediatric relapsed/refractory (R/R) acute myeloid leukemia (AML) remain dismal. CPX‐351, a liposomal formulation of cytarabine and daunorubicin, may have less off‐target toxicities than traditional chemotherapies and has shown improved outcomes for adults with newly diagnosed therapy‐related AML.
Jonathan D. Bender +17 more
wiley +1 more source
No Go Theorem for Self Tuning Solutions With Gauss-Bonnet Terms
We consider self tuning solutions for a brane embedded in an anti de Sitter spacetime. We include the higher derivative Gauss-Bonnet terms in the action and study singularity free solutions with finite effective Newton's constant.
C. Charmousis +11 more
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ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack +39 more
wiley +1 more source
A Derivative-Free Trust-Region Algorithm for Reliability-Based Optimization
In this note, we present a derivative-free trust-region (TR) algorithm for reliability based optimization (RBO) problems. The proposed algorithm consists of solving a set of subproblems, in which simple surrogate models of the reliability constraints are
Gao, Tian, Li, Jinglai
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Revision of a Derivative-Free Quasi-Newton Method [PDF]
A derivative-free Quasi-Newton (DFQN) method previously published [J. Greenstadt, Math. Comp., v. 26, 1972, pp. 145-166] has been revised and simplified. The main modification has the effect of keeping all the successive approximants to the Hessian matrix positive-definite.
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ABSTRACT Purpose Malignant rhabdoid tumor of the kidney (MRTK) is a rare, aggressive tumor seen in young children. The optimal timing of resection for locally advanced tumors is not well‐defined. The purpose of this study is to evaluate modern oncologic outcomes and the impact of surgical timing. Methods A multicenter retrospective review was performed
Hannah N. Rinehardt +76 more
wiley +1 more source
MYCN Amplification in RB1‐Inactivated Retinoblastoma: Association With High‐Risk Features
ABSTRACT Background MYCN amplification occurs in a subset of retinoblastoma cases, both with and without RB1 inactivation. It has been suggested that retinoblastomas with MYCN amplification represent a distinct entity with more aggressive clinical behavior.
Kyriaki Papaioannou +9 more
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A highly efficient new three-step derivative-free family of numerical iterative schemes for estimating all roots of polynomial equations is presented.
Mudassir Shams +5 more
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ABSTRACT Introduction Patients with ovarian cancer often present with massive ascites, leading to significant protein loss during surgical procedures. Although cell‐free concentrated ascites reinfusion therapy (CART) is used in palliative settings to mitigate protein loss, its application in intraoperative settings remains unexplored.
Yutaka Yoneoka +7 more
wiley +1 more source

